Evidence map›Paper›PMID 16762128›Full record

SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2006

A systematic review of postcoital bleeding and risk of cervical cancer.

Mark Shapley, Joanne Jordan, Peter R Croft

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  6. Postcoital bleeding.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  7. Article
  8. Colposcopic outcomes for symptomatic patients with a negative oncogenic human papillomavirus test.The Australian & New Zealand journal of obstetrics & gynaecology · 2021
    Article
  9. Article
  10. Article
  11. Cytology in the diagnosis of cervical cancer in symptomatic young women: a retrospective review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Article
  12. Delays in diagnosis of young females with symptomatic cervical cancer in England: an interview-based study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  13. Achieving earlier diagnosis of symptomatic cervical cancer.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  14. Postcoital bleeding: a review on etiology, diagnosis, and management.Obstetrics and gynecology international · 2014
    Review
  15. Article
  16. Open-access transvaginal sonography in women of reproductive age with abnormal vaginal bleeding: a descriptive study in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mark ShapleyPrimary Care Sciences Research Centre, Keele University, Staffordshire. m.shapley@cphc.keele.ac.uk
Joanne Jordan
Peter R Croft
Keele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostcoital bleeding may be a symptom of cervical cancer. Guidance to aid a GP in determining whom to investigate or refer exists but recommendations vary. Women need to be involved in decisions about their care and this involves communicating risk and an exploration of the implications of the risk. Risk estimates of postcoital bleeding for cervical cancer are not available.

aimTo provide an estimate of the positive predictive values of postcoital bleeding for cervical cancer to aid decision making in primary care about whom to investigate for cervical cancer. DESIGN OF STUDY: A systematic review.

settingCommunity, primary and secondary care.

methodSix electronic databases were searched from the beginning of each of their time frames. Inclusion criteria were that the study was published in English and reported or contained enough data to calculate the prevalence or incidence of postcoital bleeding within the study population. No studies were excluded on issues of methodological quality.

resultsThe search strategy identified 910 unique articles. The point prevalence of postcoital bleeding in the community ranged from 0.7 to 9% among women. One study reported an annual cumulative incidence of 6% of menstruating women. The prevalence of postcoital bleeding in women with cervical cancer ranged from 0.7 to 39%. Calculation of risk that a woman in the community developing postcoital bleeding has cervical cancer ranges from 1 in 44,000 at age 20-24 years to 1 in 2 400 aged 45-54 years. There was no information allowing the direct calculation of risk in women presenting to primary care.

conclusionThe evidence base for management strategies of postcoital bleeding and calculations of risk for cervical cancer in women with postcoital bleeding are poor. Recommendations for clinical practice are made on the current evidence.

Indexed as

CoitusUterine Cervical NeoplasmsAdultDecision MakingEnglandFamily PracticeFemaleHumansIncidenceMiddle AgedPractice Patterns, Physicians'PrevalenceRisk FactorsUterine Hemorrhage

Identifiers

PMID16762128
PMCPMC1839021
OpenAlexW1925716101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.