Evidence map›Paper›PMID 16760576›Full record

ReviewEndocrine pathology2006

The many faces and mimics of papillary thyroid carcinoma.

Jorge Albores-Saavedra, Jianhua Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine pathology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Pitfalls in Thyroid Cytopathology.Surgical pathology clinics · 2019
    Review
  9. Analysis of Malignant Thyroid Neoplasms with a Striking Rise of Papillary Microcarcinoma in an Endemic Goiter Region.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
    Article
  10. Article
  11. Review
  12. Article
  13. The Pathology of Hyperthyroidism.Frontiers in endocrinology · 2018
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile.Thyroid : official journal of the American Thyroid Association · 2014
    Article
  20. Absent CD56 expression in papillary thyroid carcinoma: A finding of potential diagnostic value in problematic cases of thyroid pathology.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jorge Albores-SaavedraThe Department of Pathology, Louisiana State University Health Sciences Center, Shreveport, USA. jalbor@lsu.hsc.edu
Jianhua Wu
Louisiana State University Health Sciences Center Shreveport · USLouisiana State University in Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article provides an overview of the 15 histologic variants of papillary thyroid carcinoma listed by the 2004 World Health Organization (WHO) monograph on endocrine tumors. The histologic features, differential diagnosis, and clinical course of each variant are discussed in some detail. The follicular variants (conventional and macrofollicular) constitute a morphologic challenge because the majority of these tumors are encapsulated and, also, because, in many tumors, not all neoplastic cells show the nuclear features considered to be diagnostic of papillary carcinoma. As a result, most of these tumors are missed even by experienced pathologists. Moreover, hyperplastic thyroid lesions, follicular adenomas, and Hashimoto's thyroiditis may contain cells with clear nuclei resembling those of papillary carcinoma. Papillary carcinomas composed entirely of hyperchromatic cells have been overlooked. The WHO monograph defines papillary carcinoma with focal spindle and giant cell carcinoma components but its clinical behavior is unknown. Papillary carcinoma with an insular pattern that does not show the artifactual separation of the cell nests has been misinterpreted as the solid variant of papillary carcinoma. Papillary microcarcinomas include not only the conventional type and the follicular variants but also the tall cell and columnar cell variants.

Indexed as

Adenocarcinoma, PapillaryAdenomaCell NucleusDiagnosis, DifferentialHashimoto DiseaseHumansHyperplasiaThyroid GlandThyroid NeoplasmsWorld Health Organization

Identifiers

PMID16760576
OpenAlexW2093107065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.