ReviewMicrobiology and molecular biology reviews : MMBR2006
Cyanobacterial two-component proteins: structure, diversity, distribution, and evolution.
Review in Microbiology and molecular biology reviews : MMBR, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Lysine acetylation in cyanobacteria: emerging mechanisms and functions.Biochemical Society transactions · 2025Review
- Article
- Two KaiABC systems control circadian oscillations in one cyanobacterium.Nature communications · 2024Article
- Lipids productivity of cyanobacterium Anabaena vaginicola in an internally illuminated photobioreactor using LED bar lights.Scientific reports · 2024Article
- Dynamic Changes in the Thylakoid Proteome of Cyanobacteria during Light-Regulated Thylakoid Membrane Development.Plants (Basel, Switzerland) · 2023Article
- The Transcriptional Repressor PerR Senses Sulfane Sulfur by Cysteine Persulfidation at the Structural ZnAntioxidants (Basel, Switzerland) · 2023Article
- Article
- To Die or Not to Die-Regulated Cell Death and Survival in Cyanobacteria.Microorganisms · 2022Review
- Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators.FEBS letters · 2022Article
- Expression of Scytonemin Biosynthesis Genes under Alternative Stress Conditions in the CyanobacteriumMicroorganisms · 2022Article
- The Journey from Two-Step to Multi-Step Phosphorelay Signaling Systems.Current genomics · 2021Review
- Stress Signaling in Cyanobacteria: A Mechanistic Overview.Life (Basel, Switzerland) · 2020Review
- Hik36-Hik43 and Rre6 act as a two-component regulatory system to control cell aggregation in Synechocystis sp. PCC6803.Scientific reports · 2020Article
- The Hybrid Histidine Kinase HrmK Is an Early-Acting Factor in the Hormogonium Gene Regulatory Network.Journal of bacteriology · 2020Article
- An evolutionarily conserved iron-sulfur cluster underlies redox sensory function of the Chloroplast Sensor Kinase.Communications biology · 2020Article
- We're in this Together: Sensation of the Host Cell Environment by Endosymbiotic Bacteria.Results and problems in cell differentiation · 2020Article
- Regulatory Diversity and Functional Analysis of Two-Component Systems in CyanobacteriumFrontiers in microbiology · 2020Article
- Tracing the origin and evolution of pseudokinases across the tree of life.Science signaling · 2019Article
- Proteomic De-Regulation in Cyanobacteria in Response to Abiotic Stresses.Frontiers in microbiology · 2019Review
1 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A survey of the already characterized and potential two-component protein sequences that exist in the nine complete and seven partially annotated cyanobacterial genome sequences available (as of May 2005) showed that the cyanobacteria possess a much larger repertoire of such proteins than most other bacteria. By analysis of the domain structure of the 1,171 potential histidine kinases, response regulators, and hybrid kinases, many various arrangements of about thirty different modules could be distinguished. The number of two-component proteins is related in part to genome size but also to the variety of physiological properties and ecophysiologies of the different strains. Groups of orthologues were defined, only a few of which have representatives with known physiological functions. Based on comparisons with the proposed phylogenetic relationships between the strains, the orthology groups show that (i) a few genes, some of them clustered on the genome, have been conserved by all species, suggesting their very ancient origin and an essential role for the corresponding proteins, and (ii) duplications, fusions, gene losses, insertions, and deletions, as well as domain shuffling, occurred during evolution, leading to the extant repertoire. These mechanisms are put in perspective with the different genetic properties that cyanobacteria have to achieve genome plasticity. This review is designed to serve as a basis for orienting further research aimed at defining the most ancient regulatory mechanisms and understanding how evolution worked to select and keep the most appropriate systems for cyanobacteria to develop in the quite different environments that they have successfully colonized.
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