ReviewMicrobiology and molecular biology reviews : MMBR2006
Defenses against oxidative stress in Neisseria gonorrhoeae: a system tailored for a challenging environment.
Review in Microbiology and molecular biology reviews : MMBR, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 142 citations in OpenAlex.
- Regulatory roles of the LysR-type transcriptional regulator GltC in metabolism, stress tolerance, and virulence ofMicrobiology spectrum · 2026Article
- "Let's Dry up and Survive Together": Is Anhydrobiosis in TwoInternational journal of molecular sciences · 2026Article
- The L-lactate dehydrogenase LldD contributes to oxidative stress resistance, survival from neutrophils, and host colonization inInfection and immunity · 2026Article
- Effects of legume-based rotation on subsequent sorghum rhizosphere microbial communities and their drought tolerance-related genes.Environmental microbiome · 2026Article
- Discovery of Ionophoroantibiotics as a New Antibiotic Class Targeting Metal Homeostasis in Multidrug-ResistantACS infectious diseases · 2026Article
- The CRISPR/Cas-associated scaRNA modulatesmicroLife · 2026Article
- Gentamicin induction of the gonococcalmBio · 2025Article
- Article
- Article
- Identification of novel inhibitors targeting serine acetyltransferase from Neisseria gonorrhoeae.Computational and structural biotechnology journal · 2025Article
- Transcriptional responses ofmBio · 2024Article
- Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria gonorrhoeae.PLoS pathogens · 2024Article
- Dinner date: Neisseria gonorrhoeae central carbon metabolism and pathogenesis.Emerging topics in life sciences · 2024Review
- A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation.BMC microbiology · 2024Article
- Unraveling nitrogen metabolism, cold and stress adaptation in polarFrontiers in microbiology · 2024Article
- Article
- Structural Characterization ofInternational journal of molecular sciences · 2023Article
- Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils.PLoS pathogens · 2023Article
- Zinc acquisition and its contribution toFrontiers in cellular and infection microbiology · 2023Article
- Streptococcus agalactiaemBio · 2022Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Neisseria gonorrhoeae is a host-adapted pathogen that colonizes primarily the human genitourinary tract. This bacterium encounters reactive oxygen and reactive nitrogen species as a consequence of localized inflammatory responses in the urethra of males and endocervix of females and also of the activity of commensal lactobacilli in the vaginal flora. This review describes recent advances in the understanding of defense systems against oxidative stress in N. gonorrhoeae and shows that while some of its defenses have similarities to the paradigm established with Escherichia coli, there are also some key differences. These differences include the presence of a defense system against superoxide based on manganese ions and a glutathione-dependent system for defense against nitric oxide which is under the control of a novel MerR-like transcriptional regulator. An understanding of the defenses against oxidative stress in N. gonorrhoeae and their regulation may provide new insights into the ways in which this bacterium survives challenges from polymorphonuclear leukocytes and urogenital epithelial cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.