ReviewTheoretical biology & medical modelling2006
Free radical theory of autoimmunity.
Review in Theoretical biology & medical modelling, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Adverse effect propensity: A new feature of Gulf War illness predicted by environmental exposures.iScience · 2023Article
- Serum antinuclear autoantibodies are associated with measures of oxidative stress and lifestyle factors: analysis of LIPIDOGRAM2015 and LIPIDOGEN2015 studies.Archives of medical science : AMS · 2023Article
- Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population: a nationwide observational, cross-sectional study.Rheumatology international · 2022Observational
- Design and rationale of a nationwide screening analysis from the LIPIDOGRAM2015 and LIPIDOGEN2015 studies.Archives of medical science : AMS · 2022Article
- Relationship Between Anti-DFS70 Autoantibodies and Oxidative Stress.Biomarker insights · 2022Article
- Filtration of Active Components with Antioxidant Activity Based on the Differing Antioxidant Abilities ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Evaluation of serum cancer antigen 125, resistin, leptin, homocysteine, and total antioxidant capacity in rat model of endometriosis treated with Curcumin.Physiological reports · 2019Article
- Thiol/disulphide homeostasis in celiac disease.World journal of gastrointestinal pharmacology and therapeutics · 2017Article
- Pathophysiology and Treatments of Oxidative Injury in Ischemic Stroke: Focus on the Phagocytic NADPH Oxidase 2.Antioxidants & redox signaling · 2015Review
- Proximity to traffic, ambient air pollution, and community noise in relation to incident rheumatoid arthritis.Environmental health perspectives · 2014Article
- Acquired hemophilia A: a frequently overlooked autoimmune hemorrhagic disorder.Journal of immunology research · 2014Article
- Oxidative stress is predominant in female but not in male patients with autoimmune thrombocytopenia.Oxidative medicine and cellular longevity · 2014Article
- Oxidative status and the response to pegylated-interferon alpha2a plus ribavirin in chronic genotype 4 HCV hepatitis.EXCLI journal · 2013Article
- Cytochrome-P450 enzymes and autoimmunity: expansion of the relationship and introduction of free radicals as the link.Journal of autoimmune diseases · 2009Article
- Inhalation of environmental stressors & chronic inflammation: autoimmunity and neurodegeneration.Mutation research · 2009Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
backgroundDespite great advances in clinical oncology, the molecular mechanisms underlying the failure of chemotherapeutic intervention in treating lymphoproliferative and related disorders are not well understood. HYPOTHESIS: A hypothetical scheme to explain the damage induced by chemotherapy and associated chronic oxidative stress is proposed on the basis of published literature, experimental data and anecdotal observations. Brief accounts of multidrug resistance, lymphoid malignancy, the cellular and molecular basis of autoimmunity and chronic oxidative stress are assembled to form a basis for the hypothesis and to indicate the likelihood that it is valid in vivo.
conclusionThe argument set forward in this article suggests a possible mechanism for the development of autoimmunity. According to this view, the various sorts of damage induced by chemotherapy have a role in the pattern of drug resistance, which is associated with the initiation of autoimmunity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.