Evidence map›Paper›PMID 16758408›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2006

A patient with asymptomatic severe acute respiratory syndrome (SARS) and antigenemia from the 2003-2004 community outbreak of SARS in Guangzhou, China.

Xiao-yan Che, Biao Di, Guo-ping Zhao, Ya-di Wang, Li-wen Qiu, Wei Hao, Ming Wang, Peng-zhe Qin, Yu-fei Liu, Kwok-hong Chan and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. What is the burden of asymptomatic coronavirus infections?New microbes and new infections · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. A comparative overview of COVID-19, MERS and SARS: Review article.International journal of surgery (London, England) · 2020
    Review
  18. Observational
  19. The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Xiao-yan CheCenter of Laboratory, Zhujiang Hospital, Southern Medical University, People's Republic of China.
Biao Di
Guo-ping Zhao
Ya-di Wang
Li-wen Qiu
Wei Hao
Ming Wang
Peng-zhe Qin
Yu-fei Liu
Kwok-hong Chan
Vincent C C Cheng
Kwok-yung Yuen
Guangzhou Center for Disease Control and Prevention · CNSouthern Medical University · CNUniversity of Hong Kong · HKChinese National Human Genome Center at Shanghai · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An asymptomatic case of severe acute respiratory syndrome (SARS) occurred early in 2004, during a community outbreak of SARS in Guangzhou, China. This was the first time that a case of asymptomatic SARS was noted in an individual with antigenemia and seroconversion. The asymptomatic case patient and the second index case patient with SARS in the 2003-2004 outbreak both worked in the same restaurant, where they served palm civets, which were found to carry SARS-associated coronaviruses. Epidemiological information and laboratory findings suggested that the findings for the patient with asymptomatic infection, together with the findings from previously reported serological analyses of handlers of wild animals and the 4 index case patients from the 2004 community outbreak, reflected a likely intermediate phase of animal-to-human transmission of infection, rather than a case of human-to-human transmission. This intermediate phase may be a critical stage for virus evolution and disease prevention.

Indexed as

Antigens, ViralChinaDisease OutbreaksHumansRetrospective StudiesSerologic TestsSevere Acute Respiratory SyndromeViverridaeAntigens, Viral

Identifiers

PMID16758408
PMCPMC7108013
OpenAlexW2165310577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.