Evidence map›Paper›PMID 16758113›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2006

Female-to-male transgender quality of life.

Emily Newfield, Stacey Hart, Suzanne Dibble, Lori Kohler

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05649605 (Early Mental Response to Hormonal Treatment in Transgender Men - The EMRE Study), which is not on this map. Cited by 85 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 6 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05649605 narecruitingnot on this mapstarted 2023, after this paper: background citation

Early Mental Response to Hormonal Treatment in Transgender Men - The EMRE Study

TypeinterventionalSponsorKarolinska University HospitalRan2023 to 2026Enrolled70ConditionsGender Dysphoria, Gender Identity, Gender IssuesArmsTestosterone treatment, Placebo treatment
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 6 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emily NewfieldSchool of Medicine, University of California, San Francisco, CA, USA. emily.newfield@gmail.com
Stacey Hart
Suzanne Dibble
Lori Kohler
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe evaluated health-related quality of life in female-to-male (FTM) transgender individuals, using the Short-Form 36-Question Health Survey version 2 (SF-36v2).

methodsUsing email, Internet bulletin boards, and postcards, we recruited individuals to an Internet site (http://www.transurvey.org), which contained a demographic survey and the SF36v2. We enrolled 446 FTM transgender and FTM transsexual participants, of which 384 were from the US.

resultsAnalysis of quality of life health concepts demonstrated statistically significant (p<0.01) diminished quality of life among the FTM transgender participants as compared to the US male and female population, particularly in regard to mental health. FTM transgender participants who received testosterone (67%) reported statistically significant higher quality of life scores (p<0.01) than those who had not received hormone therapy.

conclusionsFTM transgender participants reported significantly reduced mental health-related quality of life and require additional focus to determine the cause of this distress. Providing this community with the hormonal care they request is associated with improved quality of life.

Indexed as

Gender IdentityQuality of LifeAdultAndrogensDisorders of Sex DevelopmentFemaleHealth StatusHealth SurveysHumansMaleMiddle AgedSurveys and QuestionnairesTestosteroneTranssexualismAndrogensTestosterone

Identifiers

PMID16758113
OpenAlexW1996886470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.