Evidence map›Paper›PMID 16757613›Full record

ArticleJournal of clinical microbiology2006

Microsatellite analysis of three phylogenetic species of Paracoccidioides brasiliensis.

Daniel R Matute, Victoria E Sepulveda, Lina M Quesada, Gustavo H Goldman, John W Taylor, Angela Restrepo, Juan G McEwen

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. A New Duplex PCR-Assay for the Detection and Identification ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Article
  12. Molecular Tools for Detection and Identification ofJournal of fungi (Basel, Switzerland) · 2020
    Review
  13. Article
  14. Article
  15. Proteomic Analysis ofFrontiers in microbiology · 2019
    Article
  16. Species boundaries in the human pathogen Paracoccidioides.Fungal genetics and biology : FG & B · 2017
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel R MatuteCorporación para Investigaciones Biológicas (CIB), Medellín, Colombia.
Victoria E Sepulveda
Lina M Quesada
Gustavo H Goldman
John W Taylor
Angela Restrepo
Juan G McEwen

Funding

PARACOCCIDIOIDOMYCOSIS--EVOLUTION AND STRAIN-TYPINGR03TW001308 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAYLOR, JOHN W. · 2000 to 2002
$121k
FIC NIH HHS R03TW01308
6 · The paper itself

Abstract

Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, an important human systemic mycosis in Latin America. Recently, the existence of three different phylogenetic species (S1, PS2, and PS3) of P. brasiliensis was demonstrated. Despite being genetically isolated, all three species were capable of inducing disease in both humans and animals, although lower virulence has been found with the PS2 species. The available molecular methods developed to characterize and type strains have not been useful for assigning isolates to the described species, creating the need for molecular markers capable of distinguishing genetically isolated groups. Here, we describe a PCR and sequencing-based microsatellite marker system that is stable, easy to assay, adaptable to large series of isolates, and discriminatory enough to be used as a typing system in identifying the three proposed species of P. brasiliensis. In addition, this system provides an unambiguous tool for strain discrimination between two (S1 and PS2) of the three phylogenetic species.

Indexed as

Mycological Typing TechniquesPhylogenyAllelesGene FrequencyGenetic MarkersHumansMicrosatellite RepeatsMolecular Sequence DataParacoccidioidesSequence Analysis, DNASpecies SpecificityGenetic Markers

Identifiers

PMID16757613
PMCPMC1489427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.