Evidence map›Paper›PMID 16754825›Full record

Trial reportArchives of pediatrics & adolescent medicine2006

Effectiveness of nebulizer use-targeted asthma education on underserved children with asthma.

Arlene M Butz, Mona G Tsoukleris, Michele Donithan, Van Doren Hsu, Ilene Zuckerman, Kim Elizabeth Mudd, Richard E Thompson, Cindy Rand, Mary Elizabeth Bollinger

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of pediatrics & adolescent medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 8 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 8 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2011
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Improving preventive care in high risk children with asthma: lessons learned.The Journal of asthma : official journal of the Association for the Care of Asthma · 2014
    Trial
  11. Trial
  12. Trial
  13. Trial
  14. Small-group, interactive education and the effect on asthma control by children and their families.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2009
    Trial
  15. Home use of albuterol for asthma exacerbations.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2009
    Trial
  16. Article
  17. Article
  18. Review
  19. Inner city asthma.Immunology and allergy clinics of North America · 2015
    Review
  20. Factors affecting primary care provider and caregiver concordance for pediatric asthma medications.The Journal of asthma : official journal of the Association for the Care of Asthma · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Arlene M ButzDivision of General Pediatrics, Department of Pulmonary and Critical Care, The Johns Hopkins University Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA. abutz@jhmi.edu
Mona G Tsoukleris
Michele Donithan
Van Doren Hsu
Ilene Zuckerman
Kim Elizabeth Mudd
Richard E Thompson
Cindy Rand
Mary Elizabeth Bollinger
Johns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

NEBULIZER INTERVENTION IN MINORITY CHILDREN WITH ASTHMAR01NR005060 · NINR · JOHNS HOPKINS UNIVERSITY · PI BUTZ, ARLENE MANNS · 2001 to 2004
$1.9M
NINR NIH HHS NR 05060NINR NIH HHS R01 NR005060
6 · The paper itself

Abstract

objectiveTo determine the effectiveness of a home-based asthma education intervention in increasing appropriate nebulizer use and reducing symptom frequency, emergency department (ED) visits, and hospitalizations over 12 months.

designA randomized clinical trial. Settings Pediatric primary care, pulmonary/allergy, and ED practices associated with the University of Maryland Medical System and The Johns Hopkins Hospital, Baltimore.

participantsChildren with persistent asthma, aged 2 to 9 years, with regular nebulizer use and an ED visit or hospitalization within the past 12 months. Children were randomized into the intervention (n = 110) or control (n = 111) group. Follow-up data were available for 95 intervention and 86 control children.

interventionHome-based asthma education, including symptom recognition, home treatment of acute symptoms, appropriate asthma medication, and nebulizer practice.

main outcome measuresEstimates of mean differences in asthma symptom frequency, number of ED visits and hospitalizations and appropriate quick relief, controller medication, and nebulizer practice over 12 months.

resultsOf the 221 children, 181 (81.9%) completed the study. There were no significant differences in home nebulizer practice, asthma morbidity, ED visits, or hospitalizations between groups (P range, .11-.79). Although most children received appropriate nonurgent asthma care (mean, 2 visits per 6 months), more than one third of all children received at least 6 quick-relief medication prescriptions during 12 months, with no difference by group.

conclusionsA nebulizer education intervention had no effect on asthma severity or health care use. Of concern is the high quick-relief and low controller medication use in young children with asthma seen nearly every 3 months for nonurgent care.

Indexed as

Medically Underserved AreaNebulizers and VaporizersAsthmaChildChild, PreschoolEmergency Service, HospitalFemaleHealth EducationHospitalizationHumansMaleOutcome Assessment, Health Care

Identifiers

PMID16754825
PMCPMC2269706
OpenAlexW2108028158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.