ArticleArchives of disease in childhood2006
Unilateral multicystic dysplastic kidney: long term outcomes.
Article in Archives of disease in childhood, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 173 citations in OpenAlex.
- Clinical course of unilateral multicystic dysplastic kidney and contralateral kidney in Korean children: a single-center, retrospective study.Childhood kidney diseases · 2026Article
- When childhood anomalies grow up: adult-onset discovery of multicystic dysplastic kidney, a case report.BMC nephrology · 2026Article
- Paediatric multicystic dysplastic kidney disease in Cape Town, South Africa.BMC nephrology · 2025Article
- Co-occurrence of Peutz-Jeghers syndrome and unilateral multicystic dysplastic kidney: a case report.BMC nephrology · 2025Article
- Early diagnosis of solitary functioning kidney: comparing the prognosis of kidney agenesis and multicystic dysplastic kidney.Pediatric nephrology (Berlin, Germany) · 2024Article
- Predicting outcomes in children with congenital anomalies of the kidney and urinary tract.Pediatric nephrology (Berlin, Germany) · 2023Article
- Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- Outcomes of solitary functioning kidneys-renal agenesis is different than multicystic dysplastic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Retrospective evaluation of the pediatric multicystic dysplastic kidney patients: experience of two centers from southeastern TurkeyTurkish journal of medical sciences · 2021Article
- Pathophysiological clinical features of an infant with hypertension secondary to multicystic dysplastic kidney: a case report.BMC nephrology · 2021Article
- Reverse Phenotyping Maternal Cystic Kidney Disease by Diagnosis in a Newborn: Case Report and Literature Review on Neonatal Cystic Kidney Diseases.Acta medica Lituanic · 2021Article
- Towards adulthood with a solitary kidney.Pediatric nephrology (Berlin, Germany) · 2019Review
- Imaging of Kidney Cysts and Cystic Kidney Diseases in Children: An International Working Group Consensus Statement.Radiology · 2019Article
- Congenital Anomalies of the Kidney and Urinary Tract: A Clinical Review.Current treatment options in pediatrics · 2019Article
- Outcome of Multi-Cystic Dysplastic Kidneys in Children.Iranian journal of pediatrics · 2015Article
- Autosomal dominant polycystic kidney disease with ectopic unilateral multicystic dysplastic kidney.BMC nephrology · 2013Article
- Multicystic dysplastic kidney complicated by pyelonephritis.The American journal of case reports · 2013Article
- Cowden disease and multicystic dysplastic kidney: increased risk of renal cancer?Clinical kidney journal · 2012Article
- Unilateral multicystic dysplastic kidney: does initial size matter?Pediatric nephrology (Berlin, Germany) · 2012Article
- Pediatric renal diseases in the Kingdom of Saudi Arabia.World journal of pediatrics : WJP · 2012Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo report the long term follow up of children with antenatally detected unilateral multicystic dysplastic kidney (MCDK) with documentation of complications, involution rate with time, and renal function at 10 years.
methodsData were retrieved from a prospective regional registry of patients with MCDK between 1985 and 2004. Children were followed using a common protocol of investigation with follow up ultrasound scans (USS) at 2 (165 patients), 5 (117 patients), and 10 years (43 patients).
resultsSerial USS showed that 33% of the MCDK kidneys had completely involuted at 2 years of age, 47% at 5 years, and 59% at 10 years. No patients developed hypertension, significant proteinuria, or malignancy, but two developed pelviureteric junction obstruction in the contralateral kidney. Twenty seven of 143 children (19%) had vesicoureteric reflux (VUR) (96% mild to moderate VUR) into the contralateral kidney with no difference in the incidence of urinary tract infections or renal scarring between those with or without VUR. The mean estimated glomerular filtration rate (GFR) was 86.4 ml/min/1.73 m2 (range 48-125) in 31 of 43 patients followed to 10 years.
conclusionsConservative management of unilateral MCDK is justified with clinical review and infrequent USS but longer term follow up continues in the 41% still with renal remnants at 10 years and those with impaired GFR. It is suggested that the initial micturating cystogram is deferred unless abnormal USS features are present in the contralateral kidney or ureter.
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