ArticleFEBS letters2006
Expression and functional characterization of the putative protein 8b of the severe acute respiratory syndrome-associated coronavirus.
Article in FEBS letters, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The 29-nucleotide deletion in SARS-CoV: truncated versions of ORF8 are under purifying selection.BMC genomics · 2023Article
- SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions.Scientific reports · 2021Article
- SARS-CoV-2: Insights into its structural intricacies and functional aspects for drug and vaccine development.International journal of biological macromolecules · 2021Review
- Lost in deletion: The enigmatic ORF8 protein of SARS-CoV-2.Biochemical and biophysical research communications · 2021Review
- Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2.Human vaccines & immunotherapeutics · 2021Article
- SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells.Frontiers in immunology · 2021Article
- Evolutionary dynamics of the SARS-CoV-2 ORF8 accessory gene.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020Article
- The molecular virology of coronaviruses.The Journal of biological chemistry · 2020Review
- SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence.Pathogens (Basel, Switzerland) · 2020Review
- Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission.Scientific reports · 2018Article
- Article
- ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus.The Journal of infectious diseases · 2016Article
- Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination.Journal of virology · 2015Article
- Accessory proteins of SARS-CoV and other coronaviruses.Antiviral research · 2014Review
- The role of severe acute respiratory syndrome (SARS)-coronavirus accessory proteins in virus pathogenesis.Viruses · 2012Review
- SARS coronavirus 8b reduces viral replication by down-regulating E via an ubiquitin-independent proteasome pathway.Microbes and infection · 2011Article
- Translational control of the subgenomic RNAs of severe acute respiratory syndrome coronavirus.Virus genes · 2009Article
- The 29-nucleotide deletion present in human but not in animal severe acute respiratory syndrome coronaviruses disrupts the functional expression of open reading frame 8.Journal of virology · 2007Article
- Expression, post-translational modification and biochemical characterization of proteins encoded by subgenomic mRNA8 of the severe acute respiratory syndrome coronavirus.The FEBS journal · 2007Article
- Expression and functional characterization of the putative protein 8b of the severe acute respiratory syndrome-associated coronavirus.FEBS letters · 2006Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS 8b is one of the putative accessory proteins of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) with unknown functions. In this study, the cellular localization and activity of this estimated 9.6 kDa protein were examined. Confocal microscopy results indicated that SARS 8b is localized in both nucleus and cytoplasm of mammalian cells. Functional study revealed that overexpression of SARS 8b induced DNA synthesis. Coexpression of SARS 8b and SARS 6, a previously characterized SARS-CoV accessory protein, did not elicit synergistic effects on DNA synthesis.
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