Evidence map›Paper›PMID 16752214›Full record

ArticleJournal of molecular evolution2006

On the paucity of duplicated genes in Caenorhabditis elegans operons.

Andre R O Cavalcanti, Nicholas A Stover, Laura F Landweber

Abstract read
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In one paragraph

Article in Journal of molecular evolution, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Andre R O CavalcantiDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. aroc@pomona.edu
Nicholas A Stover
Laura F Landweber
Princeton University · USStanford University · US

Funding

UNDERSTANDING COMPLEX GENE EDITING SYSTEMS IN PROTISTSR01GM059708 · NIGMS · PRINCETON UNIVERSITY · PI LANDWEBER, LAURA F · 1999 to 2016
$4.4M
NIGMS NIH HHS GM59708
6 · The paper itself

Abstract

Spliced leader trans-splicing is an mRNA maturation process used by a small set of eukaryotes, including the nematode C. elegans, to cap the downstream genes of operons. We analyzed the frequency of duplication of operonic genes in C. elegans and confirmed that they are duplicated less often in the genome than monocistronic genes. Because operons account for about 15% of the genes in C. elegans, this lower duplication frequency might place a large constraint on the plasticity of the genome. Further analyses suggest that this paucity of duplicated genes results from operon organization hindering specific types of gene duplication.

Indexed as

Genes, DuplicateAnimalsCaenorhabditis elegansGene FrequencyOperonRNA Splicing

Identifiers

PMID16752214
OpenAlexW2056983169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.