ArticleJournal of muscle research and cell motility2006
Investigation of differentially expressed proteins in rat gastrocnemius muscle during denervation-reinnervation.
Article in Journal of muscle research and cell motility, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Nonlinear surface EMG analysis to detect the neuroprotective effect of citicoline in rat sciatic nerve crush injury.Medical & biological engineering & computing · 2022Article
- Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo.PLoS pathogens · 2021Article
- Isoquercitrin Delays Denervated Soleus Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation.Frontiers in physiology · 2020Article
- Absence of Signal Peptide Peptidase, an Essential Herpes Simplex Virus 1 Glycoprotein K Binding Partner, Reduces Virus InfectivityJournal of virology · 2019Article
- Isoquercitrin promotes peripheral nerve regeneration through inhibiting oxidative stress following sciatic crush injury in mice.Annals of translational medicine · 2019Article
- Changes in local capillarity of pure and hybrid MyHC muscle fiber types after nerve injury in rat extensor digitorum longus muscle (EDL).Histochemistry and cell biology · 2019Article
- Muscle wasting in patients with end-stage renal disease or early-stage lung cancer: common mechanisms at work.Journal of cachexia, sarcopenia and muscle · 2019Article
- Circulating protein synthesis rates reveal skeletal muscle proteome dynamics.The Journal of clinical investigation · 2016Article
- Calpain 3 Expression Pattern during Gastrocnemius Muscle Atrophy and Regeneration Following Sciatic Nerve Injury in Rats.International journal of molecular sciences · 2015Article
- Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry.Bioscience reports · 2014Article
- Binding of HSV-1 glycoprotein K (gK) to signal peptide peptidase (SPP) is required for virus infectivity.PloS one · 2014Article
- Proteomic changes in rat gastrocnemius muscle after botulinum toxin a injection.Annals of rehabilitation medicine · 2013Article
- iTRAQ-coupled 2D LC-MS/MS analysis on differentially expressed proteins in denervated tibialis anterior muscle of Rattus norvegicus.Molecular and cellular biochemistry · 2012Article
- Skeletal muscle proteomics: current approaches, technical challenges and emerging techniques.Skeletal muscle · 2011Article
- Neurotrophic actions of bone marrow stromal cells on primary culture of dorsal root ganglion tissues and neurons.Journal of molecular neuroscience : MN · 2010Article
- Proteomic studies of rat tibialis anterior muscle during postnatal growth and development.Molecular and cellular biochemistry · 2009Article
- Differential expression of sarcoplasmic and myofibrillar proteins of rat soleus muscle during denervation atrophy.Bioscience, biotechnology, and biochemistry · 2009Article
- Induction of muscle weakness by local inflammation: an experimental animal model.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2009Article
- The expression patterns of beta1,4 galactosyltransferase I and V mRNAs, and Galbeta1-4GlcNAc group in rat gastrocnemius muscles post sciatic nerve injury.Glycoconjugate journal · 2008Article
- Proteomic changes in rat thyroarytenoid muscle induced by botulinum neurotoxin injection.Proteomics · 2008Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To have a better insight into the molecular events involved in denervation-induced atrophy and reinnervation-induced regeneration of skeletal muscles, it is important to investigate the changes in expression levels of a great multitude of muscle proteins during the process of denervation-reinnervation. In this study, we employed an experimental model of rat sciatic nerve crush to examine the differentially expressed proteins in the rat gastrocnemius muscle at different time points (0, 1, 2, 3, 4 weeks) after sciatic nerve crush by using two-dimensional gel electrophoresis (2-DE) followed by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF-MS), collectively referred to as the modern proteomic analysis. The results showed that 16 proteins in the rat gastrocnemius muscle exhibited two distinct types of change pattern in their relative abundance: (1) The relative expression levels of 11 proteins (including alpha actin, myosin heavy chain, etc.) were decreased either within 1 or 2 weeks post-sciatic nerve injury, followed by restoration during the ensuing days until 4 weeks. (2) The other 5 proteins (including alpha enolase, beta enolase, signal peptide peptidase-like 3, etc.) displayed an up-regulation in their relative expression levels within 1 week following sciatic nerve injury, and a subsequent gradual decrease in their relative expression levels until 4 weeks. Moreover, the significance of the changes in expression levels of the 16 proteins during denervation-reinnervation has been selectively discussed.
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