ArticleBiophysical journal2006
Effects of arterial wall stress on vasomotion.
Article in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- Review
- Systems biology analysis of vasodynamics in mouse cerebral arterioles during resting state and functional hyperemia.PLoS computational biology · 2026Article
- A 3D-1D-0D multiscale model of the neuro-glial-vascular unit for synaptic and vascular dynamics in the dorsal vagal complex.Journal of mathematical biology · 2025Article
- Induction of haemodynamic travelling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging.EBioMedicine · 2025Article
- Article
- Zebrafish as a Model to Study Vascular Elastic Fibers and Associated Pathologies.International journal of molecular sciences · 2022Review
- The Origin of Vasomotion and Stochastic Resonance in Vasomotion.Frontiers in bioengineering and biotechnology · 2022Article
- Characterization of the active response of a guinea pig carotid artery.Frontiers in bioengineering and biotechnology · 2022Article
- Modulating swallowing-related functional connectivity and behaviorFrontiers in neurology · 2022Article
- Contribution of animal models toward understanding resting state functional connectivity.NeuroImage · 2021Review
- Review
- Coronary Smooth Muscle Cell Calcium Dynamics: Effects of Bifurcation Angle on Atheroprone Conditions.Frontiers in physiology · 2018Article
- Renal autoregulation in health and disease.Physiological reviews · 2015Review
- Neurovascular coupling: a parallel implementation.Frontiers in computational neuroscience · 2015Article
- Potassium buffering in the neurovascular unit: models and sensitivity analysis.Biophysical journal · 2013Article
- Multiple factors influence calcium synchronization in arterial vasomotion.Biophysical journal · 2012Article
- Multiscale FEM modeling of vascular tone: from membrane currents to vessel mechanics.IEEE transactions on bio-medical engineering · 2011Article
- Mechanical control of cation channels in the myogenic response.American journal of physiology. Heart and circulatory physiology · 2011Article
- Modeling Ca2+ signaling in the microcirculation: intercellular communication and vasoreactivity.Critical reviews in biomedical engineering · 2011Review
- Mechanisms of propagation of intercellular calcium waves in arterial smooth muscle cells.Biophysical journal · 2010Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smooth muscle and endothelial cells in the arterial wall are exposed to mechanical stress. Indeed blood flow induces intraluminal pressure variations and shear stress. An increase in pressure may induce a vessel contraction, a phenomenon known as the myogenic response. Many muscular vessels present vasomotion, i.e., rhythmic diameter oscillations caused by synchronous cytosolic calcium oscillations of the smooth muscle cells. Vasomotion has been shown to be modulated by pressure changes. To get a better understanding of the effect of stress and in particular pressure on vasomotion, we propose a model of a blood vessel describing the calcium dynamics in a coupled population of smooth muscle cells and endothelial cells and the consequent vessel diameter variations. We show that a rise in pressure increases the calcium concentration. This may either induce or abolish vasomotion, or increase its frequency depending on the initial conditions. In our model the myogenic response is less pronounced for large arteries than for small arteries and occurs at higher values of pressure if the wall thickness is increased. Our results are in agreement with experimental observations concerning a broad range of vessels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.