Evidence map›Paper›PMID 16750786›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Monitoring chemotherapy-induced cardiotoxicity: role of cardiac nuclear imaging.

Gurusher Singh Panjrath, Diwakar Jain

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. MIBG cardiac imaging compared to ejection fraction in evaluation of cardiotoxicity: a systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Pooled it
  2. How to Use Multimodality Imaging in Cardio-Oncology.Journal of cardiovascular development and disease · 2026
    Review
  3. Article
  4. Article
  5. Early detection of cancer therapy cardiotoxicity by radionuclide angiography: An update.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Cardiovascular imaging in cardio-oncology.Journal of thoracic disease · 2018
    Review
  12. Article
  13. Assessment of late anthracycline-induced cardiotoxicity byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  14. Review
  15. Doxorubicin induced heart failure: Phenotype and molecular mechanisms.International journal of cardiology. Heart & vasculature · 2016
    Article
  16. Multimodality Imaging in Cardiooncology.Journal of oncology · 2015
    Review
  17. Review
  18. Imaging of early modification in cardiomyopathy: the doxorubicin-induced model.The international journal of cardiovascular imaging · 2013
    Review
  19. Traditional and novel methods to assess and prevent chemotherapy-related cardiac dysfunction noninvasively.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gurusher Singh PanjrathDepartment of Internal Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY 10025, USA. gp2139@columbia.edu
Diwakar Jain
Drexel University · USSt. Luke's-Roosevelt Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiotoxicity may result from a range of chemotherapeutic agents. The prevalence of cardiotoxicity from certain cytotoxic agents is reported to be significantly high. In addition to serious side effects and increased long-lasting morbidity and mortality, dose limitation and suboptimal usage is an important adverse effect. Nuclear cardiac imaging has played a quintessential and important role in identifying patients at risk and in the prevention and reduction of cardiac injury resulting from cytotoxic agents. Despite exploring a number of other diagnostic imaging or biochemical tools for identification of cardiac injury, nuclear cardiac imaging in the form of radionuclide angiocardiography continues to be the most suitable and cost-effective tool for reducing the prevalence of cases of cardiac dysfunction resulting from chemotherapy. This article reviews the prevalence, mechanisms, and prevention strategies for cardiotoxicity associated with some of the commonly known cytotoxic agents and the role of nuclear cardiac imaging in its monitoring and prevention, along with recent advances in this area.

Indexed as

3-IodobenzylguanidineAnthracyclinesAntineoplastic AgentsApoptosisDose-Response Relationship, DrugDoxorubicinHeart DiseasesHumansMonitoring, PhysiologicMyocardiumNuclear MedicinePrognosisRadionuclide ImagingRiskRisk Factors3-IodobenzylguanidineAnthracyclinesAntineoplastic AgentsDoxorubicin

Identifiers

PMID16750786
OpenAlexW2076631018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.