ArticleJournal of the National Medical Association2006
Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait.
Article in Journal of the National Medical Association, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.
- Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations.American journal of human genetics · 2026Pooled it
- Review
- Experiences of family building counseling and perceptions of reproductive technology among adults with sickle cell disease.PloS one · 2026Article
- Implementation of the National Collegiate Athletic Association Sickle Cell Trait Screening Policy: Methods and Staff and Athlete Perspectives.Public health genomics · 2026Article
- Assessing current non-pharmacologic pain management practices for sickle cell disease in adults.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- From misconceptions to empowerment: assessing health and genetic literacy on thalassemia among Tunisian secondary school students.BMC public health · 2025Article
- Splenic Infarction in a Patient With Sickle Cell Trait Following High-Altitude Exposure.Cureus · 2025Article
- Beliefs negatively mediate adolescents' and adults' knowledge about sickle cell disease prevention and relationship choices; a one-center exploratory study in Central Region, Ghana.Archives of public health = Archives belges de sante publique · 2024Article
- Sickle Cell Screening in Adults: A Current Review of Point-of-Care Testing.Journal of hematology · 2024Review
- Genetic Information to Share with Parents when Newborn Screening Reveals the Presence of Sickle Cell Trait.International journal of pediatrics · 2024Article
- The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study.BMC public health · 2023Article
- Sickle Cell Disease Knowledge and Reproductive Decisions: A Saudi Cross-Sectional Study.Patient preference and adherence · 2023Article
- Acceptability to and Engagement With a Virtual Sickle Cell Trait Education Program (SCTaware): Single-Center Prospective Study.JMIR formative research · 2022Article
- Article
- A Health Literate Approach to Address Health Disparities: a Virtual Program for Parents of Children with Sickle Cell Trait.Journal of communication in healthcare · 2022Article
- Sickle cell trait and multisystem trauma: an unaddressed urgent knowledge gap.Trauma surgery & acute care open · 2022Article
- Prevalence of Hemoglobin-S and Baseline Level of Knowledge on Sickle Cell Disease Among Pregnant Women Attending Antenatal Clinics in Dar-Es-Salaam, Tanzania.Frontiers in genetics · 2022Article
- Knowledge, awareness, and attitude of premarital screening with special focus on sickle cell disease: a study from Odisha.Journal of community genetics · 2020Article
- Genetic counselling in sickle cell disease: views of single young adults in Ghana.Journal of community genetics · 2020Article
- Distribution of haemoglobin genotypes, knowledge, attitude and practices towards sickle cell disease among unmarried youths in the Buea Health District, Cameroon.The Pan African medical journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo evaluate knowledge, perceptions and the effectiveness of different sources of information about sickle cell trait (SCT) and sickle cell disease (SCD); to determine individual knowledge of SCT status.
methods28 individuals participated in three focus groups (healthcare providers, people affected by SCD or SCT, and community members). Surveyors interviewed 282 respondents within their neighborhoods.
resultsCommon themes across the focus groups included the limited general awareness of SCD and SCT, the emphasis on the benign nature of SCT rather than on future implications, and the need for public health education campaigns about SCD and SCT involving media strategies. The majority of community survey respondents (n = 243, 86.2%) had correct general knowledge about the genetic basis and severity of SCD, but only 16% (n = 45) knew their own trait status. When respondents had received information about SCD from friends and acquaintances, they were three times more likely to know their SCT status, compared with respondents who had not received information from a personal source (p < 0.01).
conclusionsDespite a screening history in the 1970s fraught with controversy, sickle cell disease management and detection can be a model for the empowerment of communities in making informed decisions about theirs and their families' futures, given the burgeoning of genetic information.
Indexed as
Identifiers
16749645PMC2569269W185680520What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.