Is the measurement of monocytes HLA-DR expression useful in patients with sepsis?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

1. Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) for sepsis: a meta-analysis.Critical care (London, England) · 2011
   Pooled it
2. Smoking, Gender, and Overweight Are Important Influencing Factors on Monocytic HLA-DR before and after Major Cancer Surgery.BioMed research international · 2017
   Trial
3. Age-related variation in the association between intraoperative dynamic cerebral autoregulation impairment proportion and postoperative neutrophil-to-lymphocyte ratio: an exploratory observational study.Frontiers in aging neuroscience · 2026
   Article
4. Lung single-cell RNA profiling reveals response of pulmonary capillary to sepsis-induced acute lung injury.Frontiers in immunology · 2024
   Article
5. Prospective multicentre study of host response signatures in neonatal sepsis in Sub Saharan Africa.Scientific reports · 2022
   Article
6. Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis.Cell death & disease · 2019
   Review
7. Diagnostic accuracy and clinical relevance of an inflammatory biomarker panel for sepsis in adult critically ill patients.Diagnostic microbiology and infectious disease · 2016
   Article
8. Immunosuppressive CD14+HLA-DRlow/- monocytes in prostate cancer.The Prostate · 2010
   Article
9. Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation.Critical care (London, England) · 2010
   Article
10. The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients.Clinics in chest medicine · 2008
    Review
11. Molecular and cellular aspects of sepsis-induced immunosuppression.Journal of molecular medicine (Berlin, Germany) · 2008
    Review
12. New immunological serum markers in bacteraemia: anti-inflammatory soluble CD163, but not proinflammatory high mobility group-box 1 protein, is related to prognosis.Clinical and experimental immunology · 2008
    Article
13. Rebuilding immunity in cancer patients.Blood cells, molecules & diseases
    Review
14. Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony.Molecular medicine (Cambridge, Mass.)
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as