ArticleIntensive care medicine2006
Sedation and analgesia in German intensive care units: how is it done in reality? Results of a patient-based survey of analgesia and sedation.
Article in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The effect of dexmedetomidine in mechanically ventilated patients with sepsis and septic shock: a meta-analysis of randomized controlled trials.Annals of medicine · 2026Pooled it
- The Effect of Dexmedetomidine as a Sedative Agent for Mechanically Ventilated Patients With Sepsis: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Pooled it
- Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation.The Cochrane database of systematic reviews · 2014Pooled it
- The incidence of sub-optimal sedation in the ICU: a systematic review.Critical care (London, England) · 2009Pooled it
- Effectiveness of an intensive care telehealth programme to improve process quality (ERIC): a multicentre stepped wedge cluster randomised controlled trial.Intensive care medicine · 2023Trial
- Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial.Critical care (London, England) · 2019Trial
- Fentanyl as pre-emptive treatment of pain associated with turning mechanically ventilated patients: a randomized controlled feasibility study.Intensive care medicine · 2016Trial
- Enteral vs. intravenous ICU sedation management: study protocol for a randomized controlled trial.Trials · 2013Trial
- How to implement monitoring tools for sedation, pain and delirium in the intensive care unit: an experimental cohort study.Intensive care medicine · 2012Trial
- Short-term sevoflurane sedation using the Anaesthetic Conserving Device after cardiothoracic surgery.Intensive care medicine · 2008Trial
- The implementation of an analgesia-based sedation protocol reduced deep sedation and proved to be safe and feasible in patients on mechanical ventilation.Revista Brasileira de terapia intensivaTrial
- Observational
- Effect of midazolam on delirium in critically ill patients: a propensity score analysis.The Journal of international medical research · 2022Article
- Use of patient-relevant outcome measures to assess the long-term effects of care bundles in the ICU: a scoping review protocol.BMJ open · 2022Article
- Observational
- Outcomes in Critically Ill Patients Sedated with Intravenous Lormetazepam or Midazolam: A Retrospective Cohort Study.Journal of clinical medicine · 2021Article
- Adult sedation and analgesia in a resource limited intensive care unit - A Systematic Review and evidence based guideline.Annals of medicine and surgery (2012) · 2021Review
- Behavior of a dual closed-loop controller of propofol and remifentanil guided by the bispectral index for postoperative sedation of adult cardiac surgery patients: a preliminary open study.Journal of clinical monitoring and computing · 2020Article
- Analgosedation of adult patients with elevated intracranial pressure : Survey of current clinical practice in Austria.Wiener klinische Wochenschrift · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study carried out the first patient-oriented survey on the practice of analgesia and sedation in German intensive care units, examining whether the goals of early spontaneous breathing and awake, cooperative patients are achieved.
designA postal survey was sent to 261 hospitals in Germany. Each hospital received three patient-oriented forms with questions regarding current agents and techniques for analgesia and sedation of a specific patient. Responses were obtained from 220 (84%) hospitals which returned 305 questionnaires.
resultsPatients' Ramsay sedation scale was significantly higher in all phases of analgesia and sedation, indicating that the patients were more deeply sedated than currently intended by the therapist. Propofol was used for most of the patients during short-term sedation (57%) and during weaning (48%). The preferred agent for sedation longer than 72[Symbol: see text]h was midazolam (66%).
conclusionThe choice of agents and techniques for analgesia and sedation in the intensive care unit thus follows the German guidelines. The fact that the patients were more deeply sedated than intended by the therapist in all phases of sedation may be due to the low use of sedation scales and clinical practice guidelines or to the lack of training in using these techniques.
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Registered trials
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