Evidence map›Paper›PMID 16741242›Full record

ArticleJournal of biomolecular techniques : JBT2006

Protein fragment domains identified using 2D gel electrophoresis/MALDI-TOF.

Maria D Person, Jianjun Shen, Angelina Traner, Sean C Hensley, Herng-Hsiang Lo, James L Abbruzzese, Donghui Li

Abstract read
In one paragraph

Article in Journal of biomolecular techniques : JBT, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Proteins are potent biomarkers to detect colon cancer progression.Saudi journal of biological sciences · 2017
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria D PersonDivision of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, Texas, USA.
Jianjun Shen
Angelina Traner
Sean C Hensley
Herng-Hsiang Lo
James L Abbruzzese
Donghui Li

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Pilot Project ProgramP30ES007784 · NIEHS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI RICHIE, ELLEN R · 1996 to 2011
$16.4M
SPORE in Pancreatic CancerP20CA101936 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ABBRUZZESE, JAMES L. · 2003 to 2009
$5.4M
Molecular Epidemiology of Pancreatic CancerR01CA098380 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, DONGHUI · 2004 to 2008
$2.6M
NCI NIH HHS P20 CA101936NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA098380NIEHS NIH HHS P30 ES007784NIEHS NIH HHS P30 ES07784
6 · The paper itself

Abstract

We previously reported a protein expression profiling experiment conducted on human pancreatic tissues using 2D gel electrophoresis and mass spectrometry. Here, 18 spots that were identified in the gel at molecular weights more than 10 kDa lower than database values are characterized. The matrix-assisted laser desorption/ionization mass spectrometry coverage is sufficient to identify the protein region present in each spot. Most of the fragments correspond to processed chains and known structural or functional domains, which may result from limited proteolysis.

Indexed as

Amino Acid SequenceElectrophoresis, Gel, Two-DimensionalEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsHumansIsoelectric PointMolecular ChaperonesMolecular Sequence DataPancreasPeptide HydrolasesPeptidesProtein ConformationProteinsProtein Structure, TertiaryProteomicsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsMolecular ChaperonesPeptide HydrolasesPeptidesProteins

Identifiers

PMID16741242
PMCPMC2291776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.