Evidence map›Paper›PMID 16737559›Full record

ReviewGenome biology2006

RNA interference has a role in regulating Drosophila telomeres.

Elena Casacuberta, Mary-Lou Pardue

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genome biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Elena CasacubertaICREA, IBMB-CSIC, Parc Científic de Barcelona, Josep Samitier 1-5, Barcelona 08028, Spain.
Mary-Lou Pardue
Institut de Biologia Molecular de Barcelona · ESMassachusetts Institute of Technology · US

Funding

HET-A, A RETROPOSON WITH A ROLE IN CHROMOSOME STRUCTURER01GM050315 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI PARDUE, MARY-LOU · 1995 to 2006
$2.3M
An Evolutionary Link Between Telomeres and TransposonsR56GM050315 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI PARDUE, MARY-LOU · 2008 to 2008
$399k
NIGMS NIH HHS GM50315NIGMS NIH HHS R01 GM050315NIGMS NIH HHS R56 GM050315
6 · The paper itself

Abstract

Unlike many other organisms, Drosophila maintains its telomeres by the transposition of retrotransposons to chromosome ends. Recent work shows that proteins in the RNA interference pathway specifically regulate the expression of these retrotransposons and frequency of transposition in germline cells, but do not affect retrotransposon expression or telomere function in the soma.

Indexed as

RetroelementsRNA InterferenceAnimalsDrosophila melanogasterDrosophila ProteinsTelomereDrosophila ProteinsRetroelements

Identifiers

PMID16737559
PMCPMC1779526
OpenAlexW2120726184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.