ReviewJournal of human genetics2006
The genetics of intracranial aneurysms.
Review in Journal of human genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Collagen Type I Alpha 2 (COL1A2) Polymorphism Contributes to Intracranial Aneurysm Susceptibility: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2017Pooled it
- Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.Neurology · 2013Pooled it
- Endothelial nitric oxide synthase rs1799983 gene polymorphism is associated with the risk of developing intracranial aneurysm.Acta neurochirurgica · 2023Article
- Lack of the human choline transporter-like protein SLC44A2 causes hearing impairment and a rare red blood phenotype.EMBO molecular medicine · 2023Article
- The Association between Genes Polymorphisms of Heparan Sulfate Proteoglycan 2 (Iranian journal of public health · 2019Review
- Rare and Low-Frequency Variant ofCirculation. Genomic and precision medicine · 2018Article
- Rho Guanine Nucleotide Exchange FactorCirculation. Genomic and precision medicine · 2018Article
- Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis.Translational stroke research · 2018Article
- A Review of the Genetics of Intracranial Berry Aneurysms and Implications for Genetic Counseling.Journal of genetic counseling · 2017Review
- RNF213 Is Associated with Intracranial Aneurysms in the French-Canadian Population.American journal of human genetics · 2016Article
- A 54-year-old man with 12 intracranial aneurysms and familial subarachnoid hemorrhage: case report.Neurosurgical review · 2016Article
- Treatment of Intracranial Aneurysms: Clipping Versus Coiling.Current cardiology reports · 2015Review
- Association of Versican (VCAN) gene polymorphisms rs251124 and rs2287926 (G428D), with intracranial aneurysm.Meta gene · 2014Article
- Smooth muscle cells and the formation, degeneration, and rupture of saccular intracranial aneurysm wall--a review of current pathophysiological knowledge.Translational stroke research · 2014Review
- Cerebral aneurysms: formation, progression, and developmental chronology.Translational stroke research · 2014Review
- Anesthetic management of patients with intracranial aneurysms.Ochsner journal · 2014Review
- Lack of association of lysyl oxidase (LOX) gene polymorphisms with intracranial aneurysm in a south Indian population.Molecular biology reports · 2013Article
- Physical factors effecting cerebral aneurysm pathophysiology.Annals of biomedical engineering · 2013Review
- The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD).Current hypertension reviews · 2013Review
- Interactions of miR-34b/c and TP53 polymorphisms on the risk of intracranial aneurysm.Clinical & developmental immunology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rupture of an intracranial aneurysm (IA) leads to a subarachnoid hemorrhage, a sudden onset disease that can lead to severe disability and death. Several risk factors such as smoking, hypertension and excessive alcohol intake are associated with subarachnoid hemorrhage. IAs, ruptured or unruptured, can be treated either surgically via a craniotomy (through an opening in the skull) or endovascularly by placing coils through a catheter in the femoral artery. Even though the etiology of IA formation is mostly unknown, several studies support a certain role of genetic factors. In reports so far, genome-wide linkage studies suggest several susceptibility loci that may contain one or more predisposing genes. Studies of several candidate genes report association with IAs. To date, no single gene has been identified as responsible for IA formation or rupture. The identification of susceptible genes may lead to the understanding of the mechanism of formation and rupture and possibly lead to the development of a pharmacological therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.