Evidence map›Paper›PMID 16735068›Full record

ArticleMolecular and biochemical parasitology2006

Expression site silencing and life-cycle progression appear normal in Argonaute1-deficient Trypanosoma brucei.

Christian J Janzen, Frederick van Deursen, Huafang Shi, George A M Cross, Keith R Matthews, Elisabetta Ullu

Abstract read
In one paragraph

Article in Molecular and biochemical parasitology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  5. The CAF1-NOT complex of trypanosomes.Frontiers in genetics · 2014
    Review
  6. Article
  7. Article
  8. The cell biology of Trypanosoma brucei differentiation.Current opinion in microbiology · 2007
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christian J Janzen *Laboratory of Molecular Parasitology, The Rockefeller University, Box 185, 1230 York Avenue, New York, NY 10021-6399, USA.
Frederick van Deursen *Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK.
Huafang ShiDepartment of Internal Medicine, Yale Medical School, BCMM 136D, 295 Congress Avenue, Box 9812, New Haven, CT, 06536-8012, USA.
George A M CrossLaboratory of Molecular Parasitology, The Rockefeller University, Box 185, 1230 York Avenue, New York, NY 10021-6399, USA.
Keith R MatthewsInstitute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK.
Elisabetta UlluDepartment of Internal Medicine, Yale Medical School, BCMM 136D, 295 Congress Avenue, Box 9812, New Haven, CT, 06536-8012, USA.

Funding

MOLECULAR GENETICS OF TRYPANOSOME ANTIGENIC VARIATIONR01AI021729 · NIAID · ROCKEFELLER UNIVERSITY · PI CROSS, GEORGE ALAN MARTIN · 1985 to 2011
$5.3M
SMALL RNAS AND THEIR ROLE IN TRYPANOSOME BIOLOGYR01AI056333 · NIAID · YALE UNIVERSITY · PI ULLU, ELISABETTA · 2003 to 2012
$3.3M
Telomere structure and function in Trypanosoma bruceiR01AI050614 · NIAID · ROCKEFELLER UNIVERSITY · PI CROSS, GEORGE ALAN MARTIN · 2002 to 2005
$1.6M
MOLECULAR GENETICS OF TRYPANOSOME ANTIGENIC VARIATIONR37AI021729 · NIAID · ROCKEFELLER UNIVERSITY · PI CROSS, GEORGE ALAN MARTIN · 1988 to 1997
–
NIAID NIH HHS AI21729NIAID NIH HHS AI50614NIAID NIH HHS AI56333NIAID NIH HHS R01 AI021729NIAID NIH HHS R01 AI050614NIAID NIH HHS R01 AI056333Wellcome Trust 073358
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RNA InterferenceAnimalsArgonaute ProteinsBloodDNA, MitochondrialGene Expression Regulation, DevelopmentalLife Cycle StagesMembrane GlycoproteinsMiceMice, Inbred BALB CProtozoan ProteinsRNA-Binding ProteinsTrypanosoma brucei bruceiTrypanosomiasis, AfricanVariant Surface Glycoproteins, TrypanosomaAGO1 protein, Trypanosoma bruceiArgonaute ProteinsDNA, MitochondrialMembrane Glycoproteinsprocyclic acidic repetitive protein, TrypanosomaProtozoan ProteinsRNA-Binding ProteinsVariant Surface Glycoproteins, Trypanosoma

Identifiers

PMID16735068
PMCPMC3904126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.