ArticleClinical and molecular allergy : CMA2006
Intestinal strongyloidiasis and hyperinfection syndrome.
Article in Clinical and molecular allergy : CMA, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 263 citations in OpenAlex.
- Fatal Disseminated Strongyloidiasis in a Patient With Untreated HIV: A Diagnostic Challenge.ACG case reports journal · 2026Article
- Predictors of severe strongyloidiasis and mortality in hospitalized patients from Southern Thailand.PLoS neglected tropical diseases · 2026Article
- Severe ARDS caused byFrontiers in medicine · 2026Article
- Duodenal Strongyloidiasis Mimicking Inflammatory Bowel Disease: A Case Report of a 52-Year-Old Immunocompetent Woman.Clinical medicine insights. Case reports · 2026Article
- Circulating Angiopoietin-like proteins in Strongyloides Stercoralis infection and reversal following treatment.PLoS neglected tropical diseases · 2025Article
- A 53-year-old woman with necrotising myopathy presenting with cough and respiratory distress: a diagnostic conundrum.Breathe (Sheffield, England) · 2025Article
- Article
- Strongyloides Hyperinfection Syndrome and Disseminated Disease with Negative Serology.The American journal of tropical medicine and hygiene · 2024Article
- Strongyloidiasis.Nature reviews. Disease primers · 2024Review
- Modifications to the parasitological technique of Rugai increase the diagnostic sensitivity for strongyloidiasis.Parasitology research · 2024Article
- A Rare Case of an Eosinophilic Pleural Effusion and Loculated Ascites Associated with Strongyloides stercoralis Hyperinfection Syndrome in California.Case reports in pulmonology · 2024Article
- An Unusual Case of LethalCase reports in infectious diseases · 2024Article
- Fatal Disseminated Strongyloidiasis in an Immunosuppressed Patient During COVID-19 Pandemic.Acta parasitologica · 2023Article
- DisseminatedBMJ case reports · 2023Article
- Efficacy of Oral Ivermectin as Empirical Prophylaxis for Strongyloidiasis in Patients Treated with High-Dose Corticosteroids: A Retrospective Cohort Study.The American journal of tropical medicine and hygiene · 2023Article
- Current and future strategies against cutaneous parasites.Pharmaceutical research · 2022Review
- Association of human disturbance and gastrointestinal parasite infection of yellow baboons in western Tanzania.PloS one · 2022Article
- Diagnostic accuracy of somatic and excretory-secretory antigens fromParasitology · 2021Article
- Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth.PLoS neglected tropical diseases · 2021Article
- Strongyloides Hyperinfection Causing Gastrointestinal Bleeding and Bacteremia in an Immunocompromised Patient.Cureus · 2021Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In spite of recent advances with experiments on animal models, strongyloidiasis, an infection caused by the nematode parasite Strongyloides stercoralis, has still been an elusive disease. Though endemic in some developing countries, strongyloidiasis still poses a threat to the developed world. Due to the peculiar but characteristic features of autoinfection, hyperinfection syndrome involving only pulmonary and gastrointestinal systems, and disseminated infection with involvement of other organs, strongyloidiasis needs special attention by the physician, especially one serving patients in areas endemic for strongyloidiasis. Strongyloidiasis can occur without any symptoms, or as a potentially fatal hyperinfection or disseminated infection. Th2 cell-mediated immunity, humoral immunity and mucosal immunity have been shown to have protective effects against this parasitic infection especially in animal models. Any factors that suppress these mechanisms (such as intercurrent immune suppression or glucocorticoid therapy) could potentially trigger hyperinfection or disseminated infection which could be fatal. Even with the recent advances in laboratory tests, strongyloidiasis is still difficult to diagnose. But once diagnosed, the disease can be treated effectively with antihelminthic drugs like Ivermectin. This review article summarizes a case of strongyloidiasis and various aspects of strongyloidiasis, with emphasis on epidemiology, life cycle of Strongyloides stercoralis, clinical manifestations of the disease, corticosteroids and strongyloidiasis, diagnostic aspects of the disease, various host defense pathways against strongyloidiasis, and available treatment options.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.