ArticleLangmuir : the ACS journal of surfaces and colloids2006
Creating advanced multifunctional biosensors with surface enzymatic transformations.
Article in Langmuir : the ACS journal of surfaces and colloids, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Nanostructured plasmonic chips employing nanopillar and nanoring hole arrays for enhanced sensitivity of SPR-based biosensing.RSC advances · 2021Article
- Early detection of bacteria using SPR imaging and event counting: experiments withRSC advances · 2019Article
- Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Electrocatalytic amplification of DNA-modified nanoparticle collisionsChemical science · 2016Article
- Surface Enzyme Chemistries for Ultrasensitive Microarray Biosensing with SPR Imaging.Langmuir : the ACS journal of surfaces and colloids · 2015Article
- Advances in plasmonic technologies for point of care applications.Chemical reviews · 2014Review
- Distance-dependent intrinsic fluorescence of proteins on aluminum nanostructures.Proceedings of SPIE--the International Society for Optical Engineering · 2012Article
- Real-Time Analysis of Specific Protein-DNA Interactions with Surface Plasmon Resonance.Journal of amino acids · 2012Article
- Feasibility of Using Bimetallic Plasmonic Nanostructures to Enhance the Intrinsic Emission of Biomolecules.The journal of physical chemistry. C, Nanomaterials and interfaces · 2011Article
- Thiolene-based microfluidic flow cells for surface plasmon resonance imaging.Biomicrofluidics · 2011Article
- Rapid microarray detection of DNA and proteins in microliter volumes with surface plasmon resonance imaging measurements.Langmuir : the ACS journal of surfaces and colloids · 2011Article
- Ultrasensitive microarray detection of short RNA sequences with enzymatically modified nanoparticles and surface plasmon resonance imaging measurements.Analytical chemistry · 2011Article
- Ultrasensitive DNA microarray biosensing via in situ RNA transcription-based amplification and nanoparticle-enhanced SPR imaging.Journal of the American Chemical Society · 2011Article
- LSPR Biosensor Signal Enhancement Using Nanoparticle-Antibody Conjugates.The journal of physical chemistry. C, Nanomaterials and interfaces · 2011Article
- Attomole detection of mesophilic DNA polymerase products by nanoparticle-enhanced surface plasmon resonance imaging on glassified gold surfaces.Journal of the American Chemical Society · 2010Article
- Fabrication of DNA microarrays with poly(L-glutamic acid) monolayers on gold substrates for SPR imaging measurements.Langmuir : the ACS journal of surfaces and colloids · 2009Article
- Self-assembled peptide monolayers as a toxin sensing mechanism within arrayed microchannels.Analytical chemistry · 2009Article
- Nanoparticle diffraction gratings for DNA detection on photopatterned glass substrates.Biointerphases · 2008Article
- Microarray methods for protein biomarker detection.The Analyst · 2008Article
- Diagnostic devices as biomaterials: a review of nucleic acid and protein microarray surface performance issues.Journal of biomaterials science. Polymer edition · 2008Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This paper summarizes our recent work on the coupling of surface enzyme chemistry and bioaffinity interactions on biopolymer microarrays for the creation of multiplexed biosensors with enhanced selectivity and sensitivity. The surface sensitive techniques of surface plasmon resonance imaging (SPRI) and surface plasmon fluorescence spectroscopy (SPFS) are used to detect the surface enzymatic transformations in real time. Three specific examples of novel coupled surface bioaffinity/surface enzymatic processes are demonstrated: (i) a surface enzymatic amplification method utilizing the enzyme ribonuclease H (RNase H) in conjunction with RNA microarrays that permits the ultrasensitive direct detection of genomic DNA at a concentration of 1 fM without labeling or PCR amplification, (ii) the use of RNA-DNA ligation chemistry to create renewable RNA microarrays from single stranded DNA microarrays, and (iii) the application of T7 RNA polymerase for the on-chip replication of RNA from double stranded DNA microarray elements. In addition, a simple yet powerful theoretical framework that includes the contributions of both enzyme adsorption and surface enzyme kinetics is used to quantitate surface enzyme reactivity. This model is successfully applied to SPRI and SPFS measurements of surface hydrolysis reactions of RNase H and Exonuclease III (Exo III) on oligonucleotide microarrays.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.