Evidence map›Paper›PMID 16728965›Full record

ArticleInternational journal of impotence research

Semiquantitative imaging measurement of baseline and vasomodulated normal prostatic blood flow using sildenafil.

J R Haaga, A Exner, B Fei, A Seftel

Abstract readCase Reports
In one paragraph

Article in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

J R HaagaDepartment of Radiology, University Hospitals of Cleveland, Cleveland, OH 44106, USA. Haaga@UHRAD.com
A Exner
B Fei
A Seftel
University Hospitals of Cleveland · USCase Western Reserve University · US

Funding

Multimodality in vivo Molecular Imaging for Prostate PDTR21CA120536 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FEI, BAOWEI · 2006 to 2007
$326k
NCI NIH HHS R21 CA120536
6 · The paper itself

Abstract

The physiologic variability of blood flow to the prostate has not been studied until this time. We report the vasoactive effects of sildenafil and phenylephrine on blood flow of the normal prostate. Sildenafil increases prostate blood flow by approximately 75% and phenylephrine reduces the flow incrementally. Administration of these drugs with dynamic contrast-enhanced magnetic resonance imaging may improve the diagnosis of cancerous tissue because according to the literature, tumor angiogenic vessels lack the vasoactive physiologic response of the normal tissue.

Indexed as

Blood Flow VelocityEphedrineHumansMagnetic Resonance ImagingMaleMiddle AgedPhosphodiesterase InhibitorsPiperazinesProstatePurinesSildenafil CitrateSulfonesVasoconstrictor AgentsVasodilator AgentsEphedrinePhosphodiesterase InhibitorsPiperazinesPurinesSildenafil CitrateSulfonesVasoconstrictor AgentsVasodilator Agents

Identifiers

PMID16728965
PMCPMC3779690
OpenAlexW2055121788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.