ArticleAntimicrobial agents and chemotherapy2006
Microdialysis study of imipenem distribution in skeletal muscle and lung extracellular fluids of Acinetobacter baumannii-infected rats.
Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Dynamic distribution of systemically administered antibiotics in orthopeadically relevant target tissues and settings.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2024Pooled it
- Penetration of ertapenem into muscle measured by in vivo microdialysis in mechanically ventilated patients.Antimicrobial agents and chemotherapy · 2011Trial
- Article
- Population Pharmacokinetic Modeling as a Tool To Characterize the Decrease in Ciprofloxacin Free Interstitial Levels Caused by Pseudomonas aeruginosa Biofilm Lung Infection in Wistar Rats.Antimicrobial agents and chemotherapy · 2017Article
- Concentrations of voriconazole in healthy and inflamed lung in rats.Antimicrobial agents and chemotherapy · 2009Article
- Lung microdialysis study of levofloxacin in rats following intravenous infusion at steady state.Antimicrobial agents and chemotherapy · 2008Article
- Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.Antimicrobial agents and chemotherapy · 2008Article
- Application of basic pharmacokinetic concepts to analysis of microdialysis data: illustration with imipenem muscle distribution.Clinical pharmacokinetics · 2008Article
- Mini-broncho-alveolar lavage: a simple and promising method for assessment of antibiotic concentration in epithelial lining fluid.Intensive care medicine · 2007Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate imipenem distribution in muscle and lung interstitial fluids of rats with Acinetobacter baumannii pulmonary infection. By combining microdialysis in blood and tissues, it was possible to demonstrate that free imipenem concentrations were virtually identical in blood, muscle, and lung.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.