Evidence map›Paper›PMID 16723598›Full record

ArticleAntimicrobial agents and chemotherapy2006

Fluoroquinolone-resistant urinary isolates of Escherichia coli from outpatients are frequently multidrug resistant: results from the North American Urinary Tract Infection Collaborative Alliance-Quinolone Resistance study.

James A Karlowsky, Daryl J Hoban, Melanie R Decorby, Nancy M Laing, George G Zhanel

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02591901 (Prevention of Recurrent Symptomatic Urinary Tract Infections in Participants With Chronic Neurogenic Bladder Dysfunction), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02591901 phase2completednot on this mapstarted 2018, after this paper: background citation

Prevention of Recurrent Symptomatic Urinary Tract Infections in Participants With Chronic Neurogenic Bladder Dysfunction: A Mixed Method Study

TypeinterventionalSponsorBuckinghamshire Healthcare NHS TrustRan2018 to 2019Enrolled48ConditionsUTI, Neurogenic Bladder, Antibiotic ResistanceArmsUro vaxom, Placebo comparator
3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. DistinctbioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  15. Article
  16. Detection of Plasmid-MediatedThe open microbiology journal · 2018
    Article
  17. Article
  18. Review
  19. Fluoroquinolone antimicrobial drugs.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Article
  20. Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James A KarlowskyDepartment of Clinical Microbiology, Health Sciences Centre/Diagnostic Services of Manitoba, Winnipeg, Canada. jkarlowsky@hsc.mb.ca
Daryl J Hoban
Melanie R Decorby
Nancy M Laing
George G Zhanel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciprofloxacin-resistant Escherichia coli isolates (n = 1,858) from outpatient midstream urine specimens at 40 North American clinical laboratories in 2004 to 2005 were frequently resistant to ampicillin (79.8% of isolates) and trimethoprim-sulfamethoxazole (66.5%); concurrent resistance to cefdinir (9.0%) or nitrofurantoin (4.0%) was less common. Only 10.8% of isolates were resistant to ciprofloxacin alone. Fluoroquinolone-resistant isolates of E. coli from urine were frequently multidrug resistant.

Indexed as

AdolescentAdultAmpicillinAnti-Infective Agents, UrinaryCefdinirCephalosporinsCiprofloxacinDrug Resistance, BacterialDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsFemaleFluoroquinolonesHumansIn Vitro TechniquesMaleAmpicillinAnti-Infective Agents, UrinaryCefdinirCephalosporinsCiprofloxacinFluoroquinolonesNitrofurantoinTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID16723598
PMCPMC1479132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.