ArticleAntimicrobial agents and chemotherapy2006
Impact of human immunodeficiency virus type 1 subtype C on drug resistance mutations in patients from Botswana failing a nelfinavir-containing regimen.
Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Subtype-specific analysis of the K65R substitution in HIV-1 that confers hypersusceptibility to a novel nucleotide-competing reverse transcriptase inhibitor.Antimicrobial agents and chemotherapy · 2015Article
- HIV-1 Genetic Variability and Clinical Implications.ISRN microbiology · 2013Article
- Directed HIV-1 evolution of protease inhibitor resistance by second-generation short hairpin RNAs.Antimicrobial agents and chemotherapy · 2012Article
- The Impact of HIV Genetic Polymorphisms and Subtype Differences on the Occurrence of Resistance to Antiretroviral Drugs.Molecular biology international · 2012Article
- Article
- HIV-1 protease codon 36 polymorphisms and differential development of resistance to nelfinavir, lopinavir, and atazanavir in different HIV-1 subtypes.Antimicrobial agents and chemotherapy · 2010Article
- HIV Genetic Diversity and Drug Resistance.Viruses · 2010Article
- Five-year follow up of genotypic resistance patterns in HIV-1 subtype C infected patients in Botswana after failure of thymidine analogue-based regimens.Journal of the International AIDS Society · 2009Article
- Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).Journal of the International AIDS Society · 2009Article
- Expression, purification and preliminary X-ray crystallographic studies of the human immunodeficiency virus 1 subtype C protease.Acta crystallographica. Section F, Structural biology and crystallization communications · 2007Article
- New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu.Retrovirology · 2007Article
- High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens.Antimicrobial agents and chemotherapy · 2006Article
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Authors and funding
14 authors.
Funding
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Abstract
Among 16 human immunodeficiency virus-infected (subtype C) Batswana patients who failed nelfinavir (NFV)-containing regimens, the most prevalent mutation observed was D30N (54%), followed by L90M (31%). L89I, K20T/I, and E35D polymorphic changes were also identified. These findings suggest that subtype C viruses in Botswana may develop resistance to NFV via subtype-specific pathways.
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Registered trials
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