ArticleEuropean child & adolescent psychiatry2006
Impaired working speed and executive functions as frontal lobe dysfunctions in young first-degree relatives of schizophrenic patients.
Article in European child & adolescent psychiatry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurocognition in youth and young adults under age 30 at familial risk for schizophrenia: a quantitative and qualitative review.Cognitive neuropsychiatry · 2013Pooled it
- Dimensions of executive functioning in schizophrenia and their relationship with processing speed.Schizophrenia bulletin · 2012Article
- Set shifting and working memory in adults with attention-deficit/hyperactivity disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2012Article
- Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort.Journal of clinical and experimental neuropsychology · 2011Article
- Premorbid cognitive deficits in young relatives of schizophrenia patients.Frontiers in human neuroscience · 2010Article
- Neurocognitive allied phenotypes for schizophrenia and bipolar disorder.Schizophrenia bulletin · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the investigation was to detect neuropsychological markers, such as sustained and selective attention and executive functions, which contribute to the vulnerability to schizophrenia especially in young persons. Performance was assessed in 32 siblings and children of schizophrenic patients and 32 matched controls using Wisconsin Card Sorting Test, Colour-Word-Interference-Test, Trail Making Test, and d2-Concentration-Test. The first-degree relatives showed certain impairments on all four tests, in particular, slower times on all time-limited tests. These results suggest the need for more time when completing neuropsychological tasks involving selected and focused attention, as well as cognitive flexibility, as a possible indicator of genetic vulnerability to schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.