ReviewImmunologic research2006
Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesis.
Review in Immunologic research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 126 citations in OpenAlex.
- PODXL2 Promotes Cholangiocarcinoma Progression via Interactions with Ezrin and Activation of the MAPK/ERK1/2 and PI3K/AKT Signaling Pathways.Digestive diseases and sciences · 2026Article
- Single-cell analysis of mesenchymal cells in permeable neural vasculature reveals novel diverse subpopulations of fibroblasts.Fluids and barriers of the CNS · 2024Article
- Glycan Modifications as Regulators of Stem Cell Fate.Biology · 2024Review
- Visualization of choroidal vasculature in pigmented mouse eyes from experimental models of AMD.Experimental eye research · 2024Article
- CD34-Structure, Functions and Relationship with Cancer Stem Cells.Medicina (Kaunas, Lithuania) · 2023Review
- Immunophenotypic characterization of acute leukemias in Bahia, Brazil.Einstein (Sao Paulo, Brazil) · 2023Article
- Endoglycan Regulates Purkinje Cell Migration by Balancing Cell-Cell Adhesion.Frontiers in neuroscience · 2022Article
- Article
- Isolation and characterization of a CD34Oncotarget · 2020Article
- Effects of Jinlongshe granules on gastric precancerous lesions in rats and its mechanism.International journal of clinical and experimental pathology · 2020Article
- The role of stem cells in treating coronary artery disease in 2018.Indian journal of thoracic and cardiovascular surgery · 2018Review
- Not just a marker: CD34 on human hematopoietic stem/progenitor cells dominates vascular selectin binding along with CD44.Blood advances · 2017Article
- Cancer stem cell marker glycosylation: Nature, function and significance.Glycoconjugate journal · 2017Review
- Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration.Experimental hematology · 2017Article
- Expansion of divergent SEA domains in cell surface proteins and nucleoporin 54.Protein science : a publication of the Protein Society · 2017Article
- Glycosylation and stem cells: Regulatory roles and application of iPSCs in the study of glycosylation-related disorders.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
- Vascular Endothelial Growth Factor and Cluster of Differentiation 34 for Assessment of Perioperative Bleeding Risk in Gastric Cancer Patients.Chinese medical journal · 2016Article
- Pathophysiology of gadolinium-associated systemic fibrosis.American journal of physiology. Renal physiology · 2016Review
- Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.Proceedings of the National Academy of Sciences of the United States of America · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CD34, podocalyxin, and endoglycan are members of a family of single-pass transmembrane proteins that show distinct expression on early hematopoietic precursors and vascular-associated tissue. In spite of the fact that the expression of CD34 on these early progenitors has been known for over 20 yr and used clinically in hematopoietic stem cell transplantation for more than 15 yr, little is known about its exact role or function. More recently, CD34 expression has been shown to distinguish activated early progenitors from quiescent cells. With the subsequent identification of podocalyxin and endoglycan as related family members also expressed on early progenitor cells, attention is slowly shifting toward understanding how these molecules might contribute to progenitor function and behavior. In this review we examine the existing evidence and propose testable models to reveal the importance of these molecules for stem and progenitor cell function.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.