Evidence map›Paper›PMID 16718813›Full record

ReviewWorld journal of gastroenterology2006

Non-steroidal anti-inflammatory drugs in prevention of gastric cancer.

Yun Dai, Wei-Hong Wang

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Article
  3. Effects of infections on the pathogenesis of cancer.The Indian journal of medical research · 2021
    Review
  4. Article
  5. Article
  6. Etiology and Prevention of Gastric Cancer.Gastrointestinal tumors · 2016
    Review
  7. Article
  8. COX-2 Inhibitors and Gastric Cancer.Gastroenterology research and practice · 2014
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yun DaiDepartment of Gastroenterology, First Hospital, Peking University, Beijing 100034, China.
Wei-Hong Wang
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) including cyclooxygenase 2 (COX-2) selective inhibitors, are potential agents for the chemoprevention of gastric cancer. Epidemiological and experimental studies have shown that NSAID use is associated with a reduced risk of gastric cancer although many questions remain unanswered such as the optimal dose and duration of treatment. The possible mechanisms for the suppressor effect of NSAIDs on carcinogenesis are the ability to induce apoptosis in epithelial cells and regulation of angiogenesis. Both COX-dependent and COX-independent pathways have a role in the biological activity of NSAIDs. Knowledge of how NSAIDs prevent neoplastic growth will greatly aid the design of better chemopreventive drugs and novel treatments for gastric cancer.

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalApoptosisCell Transformation, NeoplasticCyclooxygenase 2Cyclooxygenase 2 InhibitorsDisease Models, AnimalGene Expression Regulation, EnzymologicHelicobacter pyloriHumansNeovascularization, PathologicStomach NeoplasmsAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase 2Cyclooxygenase 2 Inhibitors

Identifiers

PMID16718813
PMCPMC4087805
OpenAlexW94544284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.