ArticleWorld journal of gastroenterology2006
Clinico-pathological aspects of colorectal serrated adenomas.
Article in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Can the rate and location of sessile serrated polyps be part of colorectal Cancer disparity in African Americans?BMC gastroenterology · 2019Article
- Screening, management and surveillance for the sessile serrated adenomas/polyps.International journal of clinical and experimental pathology · 2014Review
- Serrated colon polyps as precursors to colorectal cancer.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2013Article
- Sessile serrated adenomas: demographic, endoscopic and pathological characteristics.World journal of gastroenterology · 2010Article
- Invasive carcinomas may arise in colorectal adenomas with high-grade dysplasia and with carcinoma in situ.International journal of clinical and experimental medicine · 2010Article
- Serrated adenomas.Current gastroenterology reports · 2009Article
- Significance of serrated polyps of the colon.Current gastroenterology reports · 2008Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the association of colorectal serrated adenomas (SAs) with invasive carcinoma, local recurrence, synchronicity and metachronicity of lesions.
methodsA total of 4,536 polyps from 1,096 patients over an eight-year period (1987-1995) were retrospectively examined. Adenomas showing at least 50% of serrated architecture were called SAs by three reviewing pathologists.
resultsNinety-one (2%) of all polyps were called SAs, which were found in 46 patients. Invasive carcinomas were seen in 3 out of 46 (6.4%) patients, of whom one was a case of familial adenomatous polyposis (FAP). A male preponderance was noted and features of a mild degree of dysplasia were seen in majority (n=75, 83%) of serrated adenomas. Follow-up ranged 1-12 years with a mean time of 5.75 years. Recurrences of SAs were seen in 3 (6.4%) cases, synchronous SAs in 16 (34.8%) cases and metachronous SAs in 9 (19.6%) cases.
conclusionInvasive carcinoma arising in serrated adenoma is rare, accounting for 2 (4.3%) cases studied in this series.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.