ArticleJournal of the Association for Research in Otolaryngology : JARO2006
Planar relationships of the semicircular canals in two strains of mice.
Article in Journal of the Association for Research in Otolaryngology : JARO, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 67 citations in OpenAlex.
- Vestibular functional assessment using the caloric test in mice with arsanilic acid-induced vestibular dysfunction.Biochemistry and biophysics reports · 2026Article
- 3D X-ray microscope acts as an accurate and effective equipment of pathological diagnosis in craniofacial imaging.Scientific reports · 2024Article
- Morphology and morphometry of the inner ear of the dromedary camel and their influence on the efficiency of hearing and equilibrium.Zoological letters · 2022Article
- Implication of Vestibular Hair Cell Loss of Planar Polarity for the Canal and Otolith-Dependent Vestibulo-Ocular Reflexes inFrontiers in neuroscience · 2021Article
- Surgical techniques and functional evaluation for vestibular lesions in the mouse: unilateral labyrinthectomy (UL) and unilateral vestibular neurectomy (UVN).Journal of neurology · 2020Article
- Long term visuo-vestibular mismatch in freely behaving mice differentially affects gaze stabilizing reflexes.Scientific reports · 2020Article
- Spontaneous mutations of the Zpld1 gene in mice cause semicircular canal dysfunction but do not impair gravity receptor or hearing functions.Scientific reports · 2019Article
- Semicircular canal biomechanics in health and disease.Journal of neurophysiology · 2019Review
- Mouse Magnetic-field Nystagmus in Strong Static Magnetic Fields Is Dependent on the Presence of Nox3.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2018Article
- No Gain No Pain: Relations Between Vestibulo-Ocular Reflexes and Motion Sickness in Mice.Frontiers in neurology · 2018Article
- Wave Mechanics of the Vestibular Semicircular Canals.Biophysical journal · 2017Article
- Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery.Journal of the Association for Research in Otolaryngology : JARO · 2017Article
- Assessing morphology and function of the semicircular duct system: introducing new in-situ visualization and software toolbox.Scientific reports · 2016Article
- Shape variation and ontogeny of the ruminant bony labyrinth, an example in Tragulidae.Journal of anatomy · 2016Article
- The role of GABAB receptors in the vestibular oculomotor system in mice.Behavioural brain research · 2016Article
- Form and function of the mammalian inner ear.Journal of anatomy · 2016Review
- High-Speed Video-Oculography for Measuring Three-Dimensional Rotation Vectors of Eye Movements in Mice.PloS one · 2016Article
- The mammalian efferent vestibular system plays a crucial role in the high-frequency response and short-term adaptation of the vestibuloocular reflex.Journal of neurophysiology · 2015Article
- Synaptic diversity enables temporal coding of coincident multisensory inputs in single neurons.Nature neuroscience · 2015Article
- Dynamic characteristics of otolith ocular response during counter rotation about dual yaw axes in mice.Neuroscience · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The mouse is increasingly important as a subject of vestibular research. Although many studies have focused on the vestibular responses of mice to angular rotation, the geometry of their semicircular canals has not been described. High-voltage X-ray computed tomography was used to measure the anatomy of the semicircular canals of two strains of mice, C57Bl/6J and CBA/CaJ. The horizontal plane of a stereotaxic coordinate system was defined by the midpoints of the external auditory meati and the point where the incisors emerge from the maxilla. The centroids of the lumens of the bony canals were calculated, and planes that describe the canals were fit using a least-squares regression analysis to the resulting points. Vectors normal to each regressed plane were used to represent the corresponding canal's axis of rotation, and angles of these vectors relative to skull landmarks as well as to each other were calculated. The horizontal canal of the mouse was found to be angled anteriorly upward 17.8 degrees for CBA/CaJ and 32.6 degrees for C57Bl/6J from the reference horizontal plane. Angles between ipsilateral canals deviated up to 12.3 degrees from orthogonal, and angles between contralateral synergistic canals (left anterior-right posterior, right anterior-left posterior, and horizontal-horizontal) deviated from parallel by up to 14.8 degrees. The orientations of the canals within the head as well as the orientations of the canals relative to each other were significantly different between the two strains, suggesting that care must be taken in the design and interpretation of developmental and physiologic studies involving different mouse strains.
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