ArticleBiomedical microdevices2006
Investigation of interaction between two neutralizing monoclonal antibodies and SARS virus using biosensor based on imaging ellipsometry.
Article in Biomedical microdevices, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 59 citations in OpenAlex.
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- Taguchi method: artificial neural network approach for the optimization of high-efficiency microfluidic biosensor for COVID-19.European physical journal plus · 2023Article
- Numerical simulation and optimization of AC electrothermal microfluidic biosensor for COVID-19 detection through Taguchi method and artificial network.European physical journal plus · 2023Article
- An Insight Into Detection Pathways/Biosensors of Highly Infectious Coronaviruses.Molecular biotechnology · 2022Review
- Biosensors for the Determination of SARS-CoV-2 Virus and Diagnosis of COVID-19 Infection.International journal of molecular sciences · 2022Review
- 3D simulation of microfluidic biosensor for SARS-CoV-2 S protein binding kinetics using new reaction surface design.European physical journal plus · 2022Article
- First-Principles Simulation of Dielectric Function in Biomolecules.Materials (Basel, Switzerland) · 2021Article
- Affinity Sensors for the Diagnosis of COVID-19.Micromachines · 2021Review
- Enhancement of COVID-19 detection time by means of electrothermal force.Microfluidics and nanofluidics · 2021Article
- A computational simulation platform for designing real-time monitoring systems with application to COVID-19.Biosensors & bioelectronics · 2021Article
- An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays.Nano-micro letters · 2021Review
- Biosensor and molecular-based methods for the detection of human coronaviruses: A review.Molecular and cellular probes · 2020Review
- Nanobiosensors for the Detection of Novel Coronavirus 2019-nCoV and Other Pandemic/Epidemic Respiratory Viruses: A Review.Sensors (Basel, Switzerland) · 2020Review
- Probing antibody surface density and analyte antigen incubation time as dominant parameters influencing the antibody-antigen recognition events of a non-faradaic and diffusion-restricted electrochemical immunosensor.Analytical and bioanalytical chemistry · 2020Article
- Detection of Cytomegalovirus Antibodies Using a Biosensor Based on Imaging Ellipsometry.PloS one · 2015Article
- Joint detection of tumor markers with imaging ellipsometry biosensor.Thin solid films · 2014Article
- Analysis of interactions between SNARE proteins using imaging ellipsometer coupled with microfluidic array.Scientific reports · 2014Article
- Phage M13KO7 detection with biosensor based on imaging ellipsometry and AFM microscopic confirmation.Virus research · 2009Article
- [Application of optical proteinchip in detecting phage M13KO7].Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two neutralizing human scFv, b1 and h12 were identified initially using ELISA,employing highly purified virus as the coating antigen. The biosensor technique based on imaging ellipsometry was employed directly to detect two neutralizing monoclonal antibodies and serial serum samples from 10 SARS patients and 12 volunteers who had not SARS. Further, the kinetic process of interaction between the antibodies and SARS-CoV was studied using the real-time function of the biosensor. The biosensor is consistent with ELISA that the antibody h12 showed a higher affinity in encountering the virus than antibody b1. The affinity of antibody b1 and antibody h12 was 9.5 x 10(6) M(-1) and 1.36 x 10(7) M(- 1), respectively. As a label free method, the biosensor based on imaging ellipsometry proved to be a more competent mechanism for measuring serum samples from SARS patients and the affinity between these antibodies and the SARS coronavirus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.