Evidence map›Paper›PMID 16715212›Full record

SynthesisSurgical endoscopy2006

Comparison of laparoscopic and open ileocecal resection for Crohn's disease: a metaanalysis.

H S Tilney, V A Constantinides, A G Heriot, M Nicolaou, T Athanasiou, P Ziprin, A W Darzi, P P Tekkis

Abstract readComparative StudyMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 7 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 7 syntheses or guidelines pooled it, 190 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Crohn's disease.BMJ clinical evidence · 2011
    Pooled it
  7. Crohn's disease.BMJ clinical evidence · 2007
    Pooled it
  8. Short-term outcomes of laparoscopy combined with enhanced recovery pathway after ileocecal resection for Crohn's disease: a case-matched analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013
    Trial
  9. Laparoscopic versus open ileo-colonic resection in Crohn's disease: short- and long-term results from a prospective longitudinal study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2008
    Trial
  10. Article
  11. Article
  12. Article
  13. Revisiting fibrosis in inflammatory bowel disease: the gut thickens.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  14. Robotic Surgery in Crohn's Disease.Clinics in colon and rectal surgery · 2021
    Review
  15. Crohn's Disease Obstructions.Clinics in colon and rectal surgery · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Factors Associated with Short-Term Morbidity in Patients Undergoing Colon Resection for Crohn's Disease.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Article
  20. Pediatric Crohn's Disease.Clinics in colon and rectal surgery · 2018
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

H S TilneyDepartment of Surgical Oncology and Technology, Imperial College London, St. Mary's Hospital, 10th Floor QEQM Building, Praed Street, London, W2 1NY, UK.
V A Constantinides
A G Heriot
M Nicolaou
T Athanasiou
P Ziprin
A W Darzi
P P Tekkis
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of laparoscopic surgery for patients with ileocecal Crohn's disease is a contentious issue. This metaanalysis aimed to compare open resection with laparoscopically assisted resection for ileocecal Crohn's disease.

methodsA literature search of the Medline, Ovid, Embase, and Cochrane databases was performed to identify comparative studies reporting outcomes for both laparoscopic and open ileocecal resection. Metaanalytical techniques were applied to identify differences in outcomes between the two groups. Sensitivity analysis was undertaken to evaluate the heterogeneity of the study.

resultsOf 20 studies identified by literature review, 15 satisfied the criteria for inclusion in the study. These included outcomes for 783 patients, 338 (43.2%) of whom had undergone laparoscopic resection, with an overall conversion rate to open surgery of 6.8%. The operative time was significantly longer in the laparoscopic group, by 29.6 min (p = 0.002), although the blood loss and complications in the two groups were similar. In terms of postoperative recovery, the laparoscopic patients had a significantly shorter time for recovery of their enteric function and a shorter hospital stay, by 2.7 days (p < 0.001).

conclusionsFor selected patients with noncomplicated ileocecal Crohn's disease, laparoscopic resection offered substantial advantages in terms of more rapid resolution of postoperative ileus and shortened hospital stay. There was no increase in complications, as compared with open surgery. The contraindications to laparoscopic approaches for Crohn's disease remain undefined.

Indexed as

LaparoscopyCrohn DiseaseDigestive System Surgical ProceduresHumansIleocecal Valve

Identifiers

PMID16715212
OpenAlexW2054822000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.