Evidence map›Paper›PMID 16714444›Full record

ReviewNucleic acids research2006

The tale beyond the tail: histone core domain modifications and the regulation of chromatin structure.

Erica L Mersfelder, Mark R Parthun

Open access · goldAbstract readReview
In one paragraph

Review in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 214 citations in OpenAlex.

  1. Article
  2. Review
  3. 'Intelligent' proteins.Cellular and molecular life sciences : CMLS · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Histone H3 tail modifications required for meiosis inbioRxiv : the preprint server for biology · 2024
    Article
  9. Review
  10. Haspin mediates H3.3S31 phosphorylation downstream of Aurora B in mouse embryonic stem cells.Protein science : a publication of the Protein Society · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erica L MersfelderDepartment of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Mark R Parthun
The Ohio State University · US

Funding

Type B Histone Acetyltransferases and the Assembly of Chromatin StructureR01GM062970 · NIGMS · OHIO STATE UNIVERSITY · PI PARTHUN, MARK R · 2001 to 2018
$5.1M
NIGMS NIH HHS R01 GM062970NIGMS NIH HHS R01 GM62970
6 · The paper itself

Abstract

Histone post-translational modifications occur, not only in the N-terminal tail domains, but also in the core domains. While modifications in the N-terminal tail function largely through the regulation of the binding of non-histone proteins to chromatin, based on their location in the nucleosome, core domain modifications may also function through distinct mechanisms involving structural alterations to the nucleosome. This article reviews the recent developments in regards to these novel histone modifications and discusses their important role in the regulation of chromatin structure.

Indexed as

AnimalsHistonesHumansNucleosomesProtein Processing, Post-TranslationalHistonesNucleosomes

Identifiers

PMID16714444
PMCPMC1464108
OpenAlexW2156222068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.