ArticleEmerging infectious diseases2006
Norwalk virus-specific binding to oyster digestive tissues.
Article in Emerging infectious diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 254 citations in OpenAlex.
- Randomized, double-blinded clinical trial for human norovirus inactivation in oysters by high hydrostatic pressure processing.Applied and environmental microbiology · 2011Trial
- Occurrence of Human Enteric Viruses in Retail Mussels Marketed in Burgos, Spain.Microorganisms · 2026Article
- Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas).Glycoconjugate journal · 2025Article
- A comprehensive RNA virome identified in the oyster Magallana gigas reveals the intricate network of virus sharing between seawater and mollusks.Microbiome · 2024Article
- Role of Filter-Feeding Bivalves in the Bioaccumulation and Transmission of White Spot Syndrome Virus (WSSV) in Shrimp Aquaculture Systems.Pathogens (Basel, Switzerland) · 2024Article
- Cloning, expression and characterisation of a novel mollusc α-1,2-Fucosyltransferase from Crassostrea gigas (CgFUT2).Glycoconjugate journal · 2024Article
- Review
- Assessment of Gastroenteric Viruses in Marketed Bivalve Mollusks in the Tourist Cities of Rio de Janeiro, Brazil, 2022.Viruses · 2024Article
- Spatial Distribution and Enrichment Dynamics of Foodborne Norovirus in Oyster Tissues.Foods (Basel, Switzerland) · 2023Article
- In Vivo Evaluation of the Potential of Thyme and Lemon Hydrolates as Processing Aids to Reduce Norovirus Concentration during Oyster Depuration.Foods (Basel, Switzerland) · 2023Article
- Identification of Various InDel-II Variants of the White Spot Syndrome Virus Isolated from Frozen Shrimp and Bivalves Obtained in the Korean Commercial Market.Animals : an open access journal from MDPI · 2023Article
- Research Progress on Biological Accumulation, Detection and Inactivation Technologies of Norovirus in Oysters.Foods (Basel, Switzerland) · 2023Review
- Species-SpecificMarine drugs · 2023Article
- Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis inCurrent issues in molecular biology · 2023Article
- Temperature Dependent Depuration of Norovirus GII and Tulane Virus from Oysters (Crassostrea gigas).Food and environmental virology · 2023Article
- Bioaccumulation Dynamic by Crassostrea gigas Oysters of Viruses That Are Proposed as Surrogates for Enteric Virus Contamination in Environmental Samples.Food and environmental virology · 2023Article
- Identification of Potential Proteinaceous Ligands of GI.1 Norovirus in Pacific Oyster Tissues.Viruses · 2023Article
- Study on the Effect of Relaying on Norovirus Reduction fromMicroorganisms · 2022Article
- Clearance and persistence of Escherichia coli in the freshwater mussel Unio mancus.Scientific reports · 2022Article
- Spatial and Temporal Pattern of Norovirus Dispersal in an Oyster Growing Region in the Northeast Pacific.Viruses · 2022Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
The primary pathogens related to shellfish-borne gastroenteritis outbreaks are noroviruses. These viruses show persistence in oysters, which suggests an active mechanism of virus concentration. We investigated whether Norwalk virus or viruslike particles bind specifically to oyster tissues after bioaccumulation or addition to tissue sections. Since noroviruses attach to carbohydrates of the histo-blood group family, tests using immunohistochemical analysis were performed to evaluate specific binding of virus or viruslike particles to oyster tissues through these ligands. Viral particles bind specifically to digestive ducts (midgut, main and secondary ducts, and tubules) by carbohydrate structures with a terminal N-acetylgalactosamine residue in an alpha linkage (same binding site used for recognition of human histo-blood group antigens). These data show that the oyster can selectively concentrate a human pathogen and that conventional depuration will not eliminate noroviruses from oyster tissue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.