Trial reportPediatric nephrology (Berlin, Germany)2006
Influence of oral intake of Saccharomyces boulardii on Escherichia coli in enteric flora.
Trial report in Pediatric nephrology (Berlin, Germany), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- D-Mannose PlusMedicina (Kaunas, Lithuania) · 2023Trial
- The Management of Recurrent Urinary Tract Infection: Non-Antibiotic Bundle Treatment.Probiotics and antimicrobial proteins · 2024Article
- Article
- Management of Pediatric Urinary Tract Infections: A Delphi Study.Antibiotics (Basel, Switzerland) · 2022Article
- Update on Associated Risk Factors, Diagnosis, and Management of Recurrent Urinary Tract Infections in Children.Journal of the Pediatric Infectious Diseases Society · 2019Review
- Clinical presentation, diagnosis and treatment of vulvovaginitis in girls: a current approach and review of the literature.World journal of pediatrics : WJP · 2017Review
- Efficacy of Fluoroquinolone/Probiotic Combination Therapy for Recurrent Urinary Tract Infection in Children: A Retrospective Analysis.Clinical therapeutics · 2015Article
- Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis - a review.Clinical and experimental gastroenterology · 2015Review
- Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells.Biologics : targets & therapy · 2008Article
- Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.Pediatric nephrology (Berlin, Germany) · 2008Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteric flora constitutes 95% of the cells in the human body. It has been shown that the bacterial content of this flora is affected by diet and changes in nutrition. Considering that urinary tract infections (UTI) are mostly due to ascending infections from the gut flora, the importance of the elements of this flora and their characteristics becomes more evident. The aim of this study was to evaluate the influence of oral Saccharomyces boulardii (S. boulardii) intake on the number of Escherichia coli (E. coli) colonies in the colon. This study was carried out with 14 boys and 10 girls (total of 24 children) aged between 36 and 192 months (mean: 104.3+/-45.1 months). A commercial capsule or powder containing 5 billion colony-forming units (cfu) of S. boulardii was administered once a day for 5 days. The number of E. coli and yeast colonies was measured in the stool samples of the study group before and after the use of this drug. Before treatment, the mean number of E. coli colonies in g/ml stool was 384,625+/-445,744. This number decreased significantly to 6,283+/-20,283 after treatment (p=0.00). S. boulardii was not detected in stool before treatment and the number of colonies increased to 11,047+/-26,754 in g/ml stool. S. boulardii may be effective in reducing the number of E. coli colonies in stool. The influence of this finding on clinical practice such as prevention of UTI needs to be clarified by further studies.
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