Evidence map›Paper›PMID 16702172›Full record

ArticleHeart (British Cardiac Society)2006

Cost of cardiovascular diseases in the United Kingdom.

R Luengo-Fernández, J Leal, A Gray, S Petersen, M Rayner

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Heart (British Cardiac Society), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07213479 (Feasibility and Acceptability of Remote Home-Based Isometric Exercise and Lifestyle Change for the Management of Hypertension), which is not on this map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07213479 narecruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility and Acceptability of Remote Home-Based Isometric Exercise and Lifestyle Change for the Management of Hypertension

TypeinterventionalSponsorNorthumbria UniversityRan2026 to 2028Enrolled70ConditionsHypertension (HTN)ArmsIsometric Exercise and Lifestyle Change Advice, Lifestyle Change Advice
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 203 citations in OpenAlex.

  1. Pooled it
  2. Estimating productivity costs using the friction cost approach in practice: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2016
    Pooled it
  3. Trial
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  6. Article
  7. Article
  8. Economic burden of cardiovascular disease in the United Kingdom.European heart journal. Quality of care & clinical outcomes · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Phenomics and Robust Multiomics Data for Cardiovascular Disease Subtyping.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

R Luengo-FernándezHealth Economics Research Centre, Department of Public Health, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK. ramon.luengo-fernandez@dphpc.ox.ac.uk
J Leal
A Gray
S Petersen
M Rayner
University of Oxford · GBBritish Heart Foundation · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the economic burden of cardiovascular disease (CVD) in the United Kingdom, including health and non-healthcare costs, and the proportion of total CVD cost due to coronary heart disease (CHD) and cerebrovascular disease. DESIGN AND

settingPrevalence-based approach to assess CVD-related costs from a societal perspective. PATIENTS: All UK residents in 2004 with CVD (International classification of diseases, 10th revision (ICD-10) codes I00-I99) and subgroups with CHD (ICD-10 codes I20-I25) or cerebrovascular disease (ICD-10 codes I60-I69).

main outcome measuresHealthcare costs were estimated from expenditure on community health and social services, accident and emergency care, hospital care, rehabilitation and drugs. Non-healthcare costs were estimated from data on informal care and from productivity losses arising from morbidity and premature death.

resultsCVD cost the UK economy 29.1 billion pound in 2004, with CHD and cerebrovascular disease accounting for 29% (8.5 billion pound) and 27% (8.0 billion pound) of the total, respectively. The major cost component of CVD was health care, which accounted for 60% of the cost, followed by productivity losses due to mortality and morbidity, accounting for 23%, with the remaining 17% due to informal care-related costs.

conclusionsCVD is a leading public health problem in the UK measured by the economic burden of disease. This study identified the size and main components of that burden, and will help to inform decisions about research priorities and to monitor the impact of policy initiatives.

Indexed as

AbsenteeismCardiovascular DiseasesCost of IllnessEfficiencyHealth Care CostsHealth ExpendituresHome NursingHospital CostsHumansPrimary Health CareState Medicine

Identifiers

PMID16702172
PMCPMC1861058
OpenAlexW2146172573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.