ArticleTrials2006
Issues of informed consent for intrapartum trials: a suggested consent pathway from the experience of the Release trial [ISRCTN13204258].
Article in Trials, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04043299 (Birth Asphyxia in Uganda), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Birth Asphyxia in Uganda: Prevalence, Associated Factors and Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes
Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Questioning approaches to consent in time critical obstetric trials: findings from a mixed-methods study.BMJ open · 2024Trial
- Is a randomized controlled trial of waterbirth possible? An Australian feasibility study.Birth (Berkeley, Calif.) · 2022Trial
- Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: the GOT-IT RCT.Health technology assessment (Winchester, England) · 2019Trial
- Trial
- Trial
- Impact on caesarean section rates following injections of sterile water (ICARIS): a multicentre randomised controlled trial.BMC pregnancy and childbirth · 2013Trial
- Randomized double masked trial of Zhi Byed 11, a Tibetan traditional medicine, versus misoprostol to prevent postpartum hemorrhage in Lhasa, Tibet.Journal of midwifery & women's healthTrial
- Exploring abbreviated intrapartum consent: A mixed-methods study of patient and clinician perspectives in the Baby head ElevAtion Device trial.Clinical trials (London, England) · 2026Article
- Bridging disciplinary siloes: a scoping review on the inclusion and exclusion of pregnant and lactating populations in clinical research.BMJ public health · 2026Article
- Article
- Emergency Verbal Consent for Intrapartum Research: A Grounded Theory Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Maternity healthcare professionals' experiences of supporting women in decision-making for labour and birth: a qualitative study.BMJ open · 2024Article
- Women's and midwives' views on the optimum process for informed consent for research in a feasibility study involving an intrapartum intervention: a qualitative study.Pilot and feasibility studies · 2023Article
- Article
- Would you like to participate in this trial? The practice of informed consent in intrapartum research in the last 30 years.PloS one · 2020Article
- What women think about consent to research at the time of an obstetric emergency: a qualitative study of the views of a cohort of World Maternal Antifibrinolytic Trial participants.BJOG : an international journal of obstetrics and gynaecology · 2018Article
- Ethical issues related to consent for intrapartum trials.Reproductive health · 2017Article
- Ethical challenges posed by clinical trials in preterm labor: a case study.Reproductive health · 2017Article
- Research into a functional cure for HIV in neonates: the need for ethical foresight.The Lancet. Infectious diseases · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Service users within the NHS are increasingly being asked to participate in clinical research. In Liverpool Women's NHS Foundation Trust, approximately 35% of women take part in research during their pregnancy. For many studies the consent process is simple; information is provided and signed consent is given. There is a difficulty, however, with obtaining informed consent from women in pregnancy who become eligible only when they develop unforeseen complications, especially when they occur acutely. The problem is compounded with women in labour who may be frightened, vulnerable, in pain, under the effect of opiate analgesia, or all of the above. If research to improve the care of these women is to continue, then special consent procedures are needed. These procedures must ensure that the woman's autonomy is protected whilst recognising that women under these circumstances vary enormously, both in their desire for information and their ability to comprehend it. This paper will discuss the obtaining of consent in this situation, and describe an information and consent pathway for intrapartum research which has been developed in collaboration with consumer groups as a way in which these issues can be tackled.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.