ArticleWorld journal of gastroenterology2006
Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years' endoscopical survey.
Article in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Pooled it
- In vitro and in vivo bactericidal activity of Tinospora sagittata (Oliv.) Gagnep. var. craveniana (S.Y.Hu) Lo and its main effective component, palmatine, against porcine Helicobacter pylori.BMC complementary and alternative medicine · 2016Article
- In vitro bactericidal activity of Jinghua Weikang Capsule and its individual herb Chenopodium ambrosioides L. against antibiotic-resistant Helicobacter pylori.Chinese journal of integrative medicine · 2013Article
- Helicobacter pylori in immigrants: a "foreign" bacterium?Internal and emergency medicine · 2011Article
- Helicobacter pylori eradication: are we really all equal? A controlled study in native and immigrant population.Internal and emergency medicine · 2011Article
- Distribution of gyrA mutations in fluoroquinolone-resistant Helicobacter pylori strains.World journal of gastroenterology · 2010Article
- Helicobacter pylori vacA arrangement and related diseases: a retrospective study over a period of 15 years.Digestive diseases and sciences · 2009Article
- Endoscopic and histopathologic findings associated with H. pylori infection in very young children.Digestive diseases and sciences · 2009Article
- Prevalence of peptic ulcer in dyspeptic patients and the influence of age, sex, and Helicobacter pylori infection.Digestive diseases and sciences · 2008Article
- Managing dyspepsia in a primary care setting.Clinical medicine & research · 2006Article
- Changing disease incidence: the consulting room perspective.The British journal of general practice : the journal of the Royal College of General Practitioners · 2006Article
- Change in Prevalence and Pattern of Peptic Ulcer Disease in the Northern Savannah of Nigeria: An Endoscopic Study.Annals of African medicineArticle
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare peptic ulcer prevalence in patients referred for upper gastrointestinal endoscopy in two Italian hospitals in pre-Helicobacter era and ten years after the progressive diffusion of eradication therapy.
methodsWe checked all the endoscopic examinations consecutively performed in the Gastroenterology Unit of Padova during 1986-1987 and 1995-1996, and in the Gastroenterology Unit of Parma during 1992 and 2002. Chi Square test was used for statistic analysis.
resultsData from both the endoscopic centers showed a statistically significant decrease in the prevalence of ulcers: from 12.7% to 6.3% (P<0.001) in Padova and from 15.6% to 12% (P<0.001) in Parma. The decrease was significant both for duodenal (from 8.8% to 4.8%, P<0.001) and gastric ulcer (3.9% to 1.5%, P<0.001) in Padova, and only for duodenal ulcer in Parma (9.2% to 6.1%, P<0.001; gastric ulcer: 6.3% to 5.8%, NS).
conclusionTen years of extensive Helicobacter pylori (H pylori) eradication in symptomatic patients led to a significant reduction in peptic ulcer prevalence. This reduction was particularly evident in Padova, where a project for the sensibilization of H pylori eradication among general practioners was carried out between 1990 and 1992. Should our hypothesis be true, H pylori eradication might in the future lead to peptic ulcer as a rare endoscopic finding.
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