Evidence map›Paper›PMID 16687507›Full record

Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2006

Individual differences in reward drive predict neural responses to images of food.

John D Beaver, Andrew D Lawrence, Jenneke van Ditzhuijzen, Matt H Davis, Andrew Woods, Andrew J Calder

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 214 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 3 pooled it
33.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02841410 nacompletednot on this mapstarted 2015, after this paper: background citation

Neural Networks of Decision Making Processes Triggered by Food Labels

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2015 to 2015Enrolled35ConditionsHealthy VolunteerArmsMagnetic Resonance Imaging
NCT04051320 phase2completednot on this mapstarted 2020, after this paper: background citation

Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2020 to 2022Enrolled23ConditionsPerinatal Depression, Post Partum Depression, Depression, Postpartum, DepressionArmsLeuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 3 syntheses or guidelines pooled it, 594 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Altered default network activity in obesity.Obesity (Silver Spring, Md.) · 2011
    Trial
  17. Trial
  18. Trial
  19. Trial
  20. Article

154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John D BeaverBrain Sciences Unit, Medical Research Council Cognition, Cambridge CB2 2EF, United Kingdom. john.beaver@mrc-cbu.cam.ac.uk
Andrew D Lawrence
Jenneke van Ditzhuijzen
Matt H Davis
Andrew Woods
Andrew J Calder
Medical Research Council · GBBangor University · GB

Funding

Medical Research Council G0001237Medical Research Council G9439390Medical Research Council MC_U105579214Medical Research Council MC_U105580446
6 · The paper itself

Abstract

A network of interconnected brain regions, including orbitofrontal, ventral striatal, amygdala, and midbrain areas, has been widely implicated in a number of aspects of food reward. However, in humans, sensitivity to reward can vary significantly from one person to the next. Individuals high in this trait experience more frequent and intense food cravings and are more likely to be overweight or develop eating disorders associated with excessive food intake. Using functional magnetic resonance imaging, we report that individual variation in trait reward sensitivity (as measured by the Behavioral Activation Scale) is highly correlated with activation to images of appetizing foods (e.g., chocolate cake, pizza) in a fronto-striatal-amygdala-midbrain network. Our findings demonstrate that there is considerable personality-linked variability in the neural response to food cues in healthy participants and provide important insight into the neurobiological factors underlying vulnerability to certain eating problems (e.g., hyperphagic obesity).

Indexed as

FoodRewardAdultBrainCuesEvoked Potentials, VisualFemaleHumansMagnetic Resonance ImagingMaleNerve NetVisual Perception

Identifiers

PMID16687507
PMCPMC6674259
OpenAlexW2136519562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.