Evidence map›Paper›PMID 16687262›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2006

Reproductive health of Gulf War veterans.

Patricia Doyle, Noreen Maconochie, Margaret Ryan

Open access · greenAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Gulf War Women's Health Cohort: Study Design and Protocol.International journal of environmental research and public health · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Healthcare utilization and mortality among veterans of the Gulf War.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006
    Review
  11. Reflections on Gulf War illness.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006
    Article
  12. Toxicological assessments of Gulf War veterans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Patricia DoyleDepartment of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, UK. pat.doyle@lshtm.ac.uk
Noreen Maconochie
Margaret Ryan
London School of Hygiene & Tropical Medicine · GBUnited States Department of Defense · USUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review we summarize the scientific literature on reproductive health following deployment to the first Gulf war by armed service personnel. All the studies examined had methodological limitations, making interpretation difficult. Nonetheless we conclude that for male veterans there is no strong or consistent evidence to date for an effect of service in the first Gulf war on the risk of major, clearly defined, birth defects or stillbirth in offspring conceived after deployment. Effects on specific rare defects cannot be excluded at this stage since none of the studies had the statistical power to examine them. For miscarriage and infertility, there is some evidence of small increased risks associated with service, but the role of bias is likely to be strong. For female veterans, there is insufficient information to make robust conclusions, although the weight of evidence to date does not indicate any major problem associated specifically with deployment to the Gulf. None of the studies have been able to examine risk according particular exposures, and so possible associations with specific exposures for smaller groups of exposed veterans cannot be excluded. We suggest that the way forward to address the question of veterans' reproductive health with confidence in the future is prospective surveillance following deployment. Anything less will result in further problems of interpretation and continued anxiety for parents, as well as prospective parents, in the armed forces.

Indexed as

Gulf WarCongenital AbnormalitiesFemaleHumansInfertilityPregnancyPregnancy OutcomeVeterans

Identifiers

PMID16687262
PMCPMC1569619
OpenAlexW2109612869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.