Evidence map›Paper›PMID 16684726›Full record

ArticleHealth affairs (Project Hope)

Prices, profits, and innovation: examining criticisms of new psychotropic drugs' value.

Haiden A Huskamp

Abstract read
In one paragraph

Article in Health affairs (Project Hope). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. What is the value of 'me-too' drugs?Health care management science · 2013
    Article
  5. Review
  6. Review
  7. Article
  8. [Scientific evidence and the cost of innovations in the health-care system].Medizinische Klinik (Munich, Germany : 1983) · 2009
    Article
  9. Article
  10. Who are the new users of antipsychotic medications?Psychiatric services (Washington, D.C.) · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Haiden A HuskampHarvard Medical School, Boston, Massachusetts, USA. huskamp@hcp.med.harvard.edu

Funding

Economics of Formulary Design and Mental Health PolicyK01MH066109 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI HUSKAMP, HAIDEN A. · 2002 to 2006
$705k
NIMH NIH HHS K01 MH066109NIMH NIH HHS K01 MH66109
6 · The paper itself

Abstract

High profits and high drug costs have brought increased scrutiny of the pharmaceutical industry over the issue of whether the drugs they produce are worth the costs. I examine several related complaints, including the proliferation of me-too drugs and product reformulations, which some argue have little value relative to their cost; the baseless promotion of newer drug classes as more effective than existing, less expensive drugs; legal strategies to extend market exclusivity that result in high brand-name drug prices for an extended period of time; and large promotional expenditures that result in higher prices.

Indexed as

Drug CostsEconomic CompetitionDrug IndustryDrugs, GenericHealth Care SectorHumansMarketingPatents as TopicPsychotropic DrugsRegression AnalysisUnited StatesDrugs, GenericPsychotropic Drugs

Identifiers

PMID16684726
PMCPMC2430611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.