ReviewPediatric nephrology (Berlin, Germany)2006
Role of with-no-lysine [K] kinases in the pathogenesis of Gordon's syndrome.
Review in Pediatric nephrology (Berlin, Germany), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Article
- Deletion of Kir5.1 Impairs Renal Ability to Excrete Potassium during Increased Dietary Potassium Intake.Journal of the American Society of Nephrology : JASN · 2019Article
- Hyperkalemia in young children: blood pressure checked?European journal of pediatrics · 2016Article
- Developmental changes in renal tubular transport-an overview.Pediatric nephrology (Berlin, Germany) · 2015Review
- Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK.Biochemistry · 2015Article
- [Electrolyte disorders as a hallmark of monogenetic diseases].Der Internist · 2015Article
- Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.The Journal of biological chemistry · 2012Article
- Familial Hyperkalemic Hypertension: A New Early-onset Pediatric Case.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2012Article
- WNK1 is required for mitosis and abscission.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- The WNKs: atypical protein kinases with pleiotropic actions.Physiological reviews · 2011Review
- Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.The Journal of biological chemistry · 2010Article
- Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.The Journal of biological chemistry · 2010Article
- Metabolic acidosis: pathophysiology, diagnosis and management.Nature reviews. Nephrology · 2010Review
- WNK kinases and blood pressure control.Current hypertension reports · 2009Review
- LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension.The Journal of biological chemistry · 2009Article
- Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II.The Journal of clinical investigation · 2008Article
- WNK kinases and renal sodium transport in health and disease: an integrated view.Hypertension (Dallas, Tex. : 1979) · 2008Review
- The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.The Journal of clinical investigation · 2007Article
- SLC26A9 is a Cl(-) channel regulated by the WNK kinases.The Journal of physiology · 2007Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Gordon's syndrome, also known as pseudohypoaldosteronism type II (PHA II) or familial hypertension with hyperkalemia, is an autosomal-dominant disease characterized by hypertension, hyperkalemia, hyperchloremic metabolic acidosis, and normal glomerular filtration rate. Recent positional cloning has linked mutations of WNK1 and WNK4 to Gordon's syndrome. With-no-lysine [K] (WNK) kinases are a new family of large serine-threonine protein kinases with an atypical placement of the catalytic lysine. Here, we review the pathogenesis of PHA II based on current understanding of the actions of WNK1 and WNK4 on Na+ and K+ handling in the renal distal tubule.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.