ArticleProceedings of the National Academy of Sciences of the United States of America2006
Ripening in the tomato Green-ripe mutant is inhibited by ectopic expression of a protein that disrupts ethylene signaling.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
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84 citing papers in PubMed, 225 citations in OpenAlex.
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- Metabolomics to understand metabolic regulation underpinning fruit ripening, development, and quality.Journal of experimental botany · 2024Review
- Vegetable biology and breeding in the genomics era.Science China. Life sciences · 2023Review
- De Novo Assembly of a Sarcocarp Transcriptome Set Identifies AaMYB1 as a Regulator of Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2022Article
- A molecular framework of ethylene-mediated fruit growth and ripening processes in tomato.The Plant cell · 2022Article
- Arabidopsis CPR5 plays a role in regulating nucleocytoplasmic transport of mRNAs in ethylene signaling pathway.Plant cell reports · 2022Article
- De novo assembly of a fruit transcriptome set identifies AmMYB10 as a key regulator of anthocyanin biosynthesis in Aronia melanocarpa.BMC plant biology · 2022Article
- Atypical Climacteric and Functional Ethylene Metabolism and Signaling During Fruit Ripening in Blueberry (Frontiers in plant science · 2022Article
- Atlas of phenotypic, genotypic and geographical diversity present in the European traditional tomato.Horticulture research · 2022Article
- APETALA2/ethylene responsive factor in fruit ripening: Roles, interactions and expression regulation.Frontiers in plant science · 2022Review
- Effect of Elevated Temperature on Tomato Post-Harvest Properties.Plants (Basel, Switzerland) · 2021Article
- Novel Translational and Phosphorylation Modification Regulation Mechanisms of Tomato (International journal of molecular sciences · 2021Article
- Genome-wide binding analysis of the tomato transcription factor SlDof1 reveals its regulatory impacts on fruit ripening.Molecular horticulture · 2021Article
- Skin colour, carotenogenesis and chlorophyll degradation mutant alleles: genetic orchestration behind the fruit colour variation in tomato.Plant cell reports · 2021Review
- Transcriptional analysis reveals sodium nitroprusside affects alfalfa in response to PEG-induced osmotic stress at germination stage.Protoplasma · 2020Article
- Re-evaluation of the nor mutation and the role of the NAC-NOR transcription factor in tomato fruit ripening.Journal of experimental botany · 2020Article
- Ethylene signaling in plants.The Journal of biological chemistry · 2020Review
- Genome-wide identification of long non-coding RNA targets of the tomato MADS box transcription factor RIN and function analysis.Annals of botany · 2019Article
24 more citing papers are in PubMed but not listed here.
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2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
To achieve full ripening, climacteric fruits, such as tomato require synthesis, perception and signal transduction of the plant hormone ethylene. The nonripening phenotype of the dominant Green-ripe (Gr) and Never-ripe 2 (Nr-2) mutants of tomato is the result of reduced ethylene responsiveness in fruit tissues. In addition, a subset of ethylene responses associated with floral senescence, abscission, and root elongation are also impacted in mutant plants, but to a lesser extent. Using positional cloning, we have identified an identical 334-bp deletion in a gene of unknown biochemical function at the Gr/Nr-2 locus. Consistent with a dominant gain of function mutation, this deletion causes ectopic expression of Gr/Nr-2, which in turn leads to ripening inhibition. A CaMV35::GR transgene recreates the Gr/Nr-2 mutant phenotype but does not lead to a global reduction in ethylene responsiveness, suggesting tissue-specific modulation of ethylene responses in tomato. Gr/Nr-2 encodes an evolutionary conserved protein of unknown biochemical function that we associate here with ethylene signaling. Because Gr/Nr-2 has no sequence homology with the previously described Nr (Never-ripe) ethylene receptor of tomato we now refer to this gene only as GR. Identification of GR expands the current repertoire of ethylene signaling components in plants and provides a tool for further elucidation of ethylene response mechanisms and for controlling ethylene signal specificity in crop plants.
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