GuidelineEuropean child & adolescent psychiatry2006
Long-acting medications for the hyperkinetic disorders. A systematic review and European treatment guideline.
Guideline in European child & adolescent psychiatry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04964427 (The Effects of Methylphenidate), which is not on this map. Cited by 139 papers, 15 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Methylphenidate (MPH) and Non-invasive Brain Stimulation (tDCS) on Inhibitory Control Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
Who cites it
139 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- Association of ADHD medications with the risk of cardiovascular diseases: a meta-analysis.European child & adolescent psychiatry · 2019Pooled it
- Comparative efficacy and safety of attention-deficit/hyperactivity disorder pharmacotherapies, including guanfacine extended release: a mixed treatment comparison.European child & adolescent psychiatry · 2017Pooled it
- Pooled it
- Sweat it out? The effects of physical exercise on cognition and behavior in children and adults with ADHD: a systematic literature review.Journal of neural transmission (Vienna, Austria : 1996) · 2017Pooled it
- Omega-3 fatty acid and ADHD: blood level analysis and meta-analytic extension of supplementation trials.Clinical psychology review · 2014Pooled it
- Pooled it
- Long-acting methylphenidate formulations in the treatment of attention-deficit/hyperactivity disorder: a systematic review of head-to-head studies.BMC psychiatry · 2013Pooled it
- Treatment discontinuation with methylphenidate in adults with attention deficit hyperactivity disorder: a meta-analysis of randomized clinical trials.European journal of clinical pharmacology · 2013Pooled it
- Cost effectiveness of pharmacotherapies for attention-deficit hyperactivity disorder: a systematic literature review.CNS drugs · 2012Pooled it
- European guidelines on managing adverse effects of medication for ADHD.European child & adolescent psychiatry · 2011Guideline
- The impact of medications on quality of life in attention-deficit hyperactivity disorder: a systematic review.CNS drugs · 2010Pooled it
- Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis.European child & adolescent psychiatry · 2010Pooled it
- The quality of life of children with attention deficit/hyperactivity disorder: a systematic review.European child & adolescent psychiatry · 2010Pooled it
- Efficacy and safety of atomoxetine for attention-deficit/hyperactivity disorder in children and adolescents-meta-analysis and meta-regression analysis.Psychopharmacology · 2007Pooled it
- Comparing the efficacy of medications for ADHD using meta-analysis.MedGenMed : Medscape general medicine · 2006Pooled it
- Effects of Mobile Neurofeedback on Theta-Gamma Coupling and Clinical Outcomes in Children with ADHD: A Double-Blind, Sham-Controlled Randomized Clinical Trial.Neuropsychiatric disease and treatment · 2025Trial
- Selective Effects of Methylphenidate on Attention and Inhibition in 22q11.2 Deletion Syndrome: Results From a Clinical Trial.The international journal of neuropsychopharmacology · 2022Trial
- Methylphenidate-Related Improvements in Math Performance Cannot Be Explained by Better Cognitive Functioning or Higher Academic Motivation: Evidence From a Randomized Controlled Trial.Journal of attention disorders · 2020Trial
- Long-term Effects of Multimodal Treatment on Adult Attention-Deficit/Hyperactivity Disorder Symptoms: Follow-up Analysis of the COMPAS Trial.JAMA network open · 2019Trial
- Trial
79 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A systematic review of published and unpublished data on the use of long-acting medications in ADHD and hyperkinetic disorder is reported, giving effect sizes and numbers-to-treat for extended-release stimulant preparations and atomoxetine (ATX). A panel of experts from several European countries used the review to make recommendations about the use of these drugs in practice, and conclusions are reported: (1) Long-acting preparations should be available and used; (2) They should not replace short-acting drugs (which will be the initial treatment for many children for reasons of cost and flexibility of dosing). Individual clinical choice is needed. (3) Both ATX and extended-release preparations of stimulants should be available. The choice will depend upon the circumstances, and detailed recommendations are made.
Indexed as
Identifiers
16680409What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.