ArticleEnvironmental health perspectives2006
Calcium:magnesium ratio in local groundwater and incidence of acute myocardial infarction among males in rural Finland.
Article in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Dietary calcium intake and mortality risk from cardiovascular disease and all causes: a meta-analysis of prospective cohort studies.BMC medicine · 2014Pooled it
- Relationship between calcium-to-magnesium ratio and malaria parasite density among children with uncomplicated malaria infection.African health sciences · 2024Article
- High manganese and nickel concentrations in human hair and well water and low calcium concentration in blood serum in a pristine area with sulphide-rich bedrock.Environmental geochemistry and health · 2022Article
- Hydrochemical characterization of groundwater quality using chemometric analysis and water quality indices in the foothills of Himalayas.Environment, development and sustainability · 2022Article
- Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases.Nutrients · 2022Article
- Magnesium Status and Calcium/Magnesium Ratios in a Series of Cystic Fibrosis Patients.Nutrients · 2022Article
- Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.Sleep · 2022Article
- Assessment of the Evolution of Groundwater Chemistry and Its Controlling Factors in the Huangshui River Basin of Northwestern China, Using Hydrochemistry and Multivariate Statistical Techniques.International journal of environmental research and public health · 2021Article
- Spatial distribution of under immunization among children 12-23 months old in Butajira HDSS, southern Ethiopia.BMC pediatrics · 2021Article
- Groundwater Pollution Sources Apportionment in the Ghaen Plain, Iran.International journal of environmental research and public health · 2018Article
- Evaluation of the Predictive Value of the Serum Calcium-Magnesium Ratio for All-Cause and Cardiovascular Mortality in Incident Dialysis Patients.Cardiorenal medicine · 2017Article
- Impact of Calcium and Magnesium in Groundwater and Drinking Water on the Health of Inhabitants of the Slovak Republic.International journal of environmental research and public health · 2017Article
- Chemical composition of groundwater and relative mortality for cardiovascular diseases in the Slovak Republic.Environmental geochemistry and health · 2015Article
- Relationship between tap water hardness, magnesium, and calcium concentration and mortality due to ischemic heart disease or stroke in The Netherlands.Environmental health perspectives · 2010Article
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Several epidemiologic studies have shown an association between calcium and magnesium and coronary heart disease mortality and morbidity. In this small-area study, we examined the relationship between acute myocardial infarction (AMI) risk and content of Ca, Mg, and chromium in local groundwater in Finnish rural areas using Bayesian modeling and geospatial data aggregated into 10 km times symbol 10 km grid cells. Data on 14,495 men 35-74 years of age with their first AMI in the years 1983, 1988, or 1993 were pooled. Geochemical data consisted of 4,300 measurements of each element in local groundwater. The median concentrations of Mg, Ca, and Cr and the Ca:Mg ratio in well water were 2.61 mg/L, 12.23 mg/L, 0.27 microg/L, and 5.39, respectively. Each 1 mg/L increment in Mg level decreased the AMI risk by 4.9%, whereas a one unit increment in the Ca:Mg ratio increased the risk by 3.1%. Ca and Cr did not show any statistically significant effect on the incidence and spatial variation of AMI. Results of this study with specific Bayesian statistical analysis support earlier findings of a protective role of Mg and low Ca:Mg ratio against coronary heart disease but do not support the earlier hypothesis of a protective role of Ca.
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