ReviewJournal of biomedical optics
Optical coherence tomography for imaging the vulnerable plaque.
Review in Journal of biomedical optics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed.
- Optical coherence tomography of the newborn airway.The Annals of otology, rhinology, and laryngology · 2008Trial
- Computational Analysis of Intravascular OCT Images for Future Clinical Support: A Comprehensive Review.IEEE reviews in biomedical engineering · 2026Review
- Article
- Optical imaging guidance in oncologic surgery and interventional oncology.Pharmacological research · 2025Review
- Validation of biomechanical assessment of coronary plaque vulnerability based on intravascular optical coherence tomography and digital subtraction angiography.Quantitative imaging in medicine and surgery · 2024Article
- OCT Guidance in Bifurcation Percutaneous Coronary Intervention.Reviews in cardiovascular medicine · 2023Review
- Intravascular polarization-sensitive optical coherence tomography based on polarization mode delay.Scientific reports · 2022Article
- Non-invasive Multimodality Imaging of Coronary Vulnerable Patient.Frontiers in cardiovascular medicine · 2022Review
- Optical Coherence Tomography of Plaque Vulnerability and Rupture: JACC Focus Seminar Part 1/3.Journal of the American College of Cardiology · 2021Review
- Optical coherence tomography of small intestine allograft biopsies using a handheld surgical probe.Journal of biomedical optics · 2021Article
- Advances in Endoscopic Photoacoustic Imaging.Photonics · 2021Article
- Mechanically Rotating Intravascular Ultrasound (IVUS) Transducer: A Review.Sensors (Basel, Switzerland) · 2021Review
- Gender-basedJournal of cardiovascular and thoracic research · 2021Article
- A Metabolic Intravascular Platform to Study FDG Uptake in Vascular Injury.Cardiovascular engineering and technology · 2020Article
- OCT-NIRS Imaging for Detection of Coronary Plaque Structure and Vulnerability.Frontiers in cardiovascular medicine · 2020Review
- Interference-free Detection of Lipid-laden Atherosclerotic Plaques by 3D Co-registration of Frequency-Domain Differential Photoacoustic and Ultrasound Radar Imaging.Scientific reports · 2019Article
- Vulnerable Plaque, Characteristics, Detection, and Potential Therapies.Journal of cardiovascular development and disease · 2019Review
- Frequency-domain differential photoacoustic radar: theory and validation for ultrasensitive atherosclerotic plaque imaging.Journal of biomedical optics · 2019Article
- Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes.Scientific reports · 2018Article
- A Novel Mach-Zehnder Interferometer Using Eccentric-Core Fiber Design for Optical Coherence Tomography.Sensors (Basel, Switzerland) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
While our understanding of vulnerable coronary plaque is still at an early stage, the concept that certain types of plaques predispose patients to developing an acute myocardial infarction continues to be at the forefront of cardiology research. Intracoronary optical coherence tomography (OCT) has been developed to both identify and study these lesions due to its distinct resolution advantage over other imaging modalities. We review clinical research conducted at the Massachusetts General Hospital over the past five years to develop, validate, and utilize this technology to improve our understanding of vulnerable plaque. Our results show that intracoronary OCT may be safely conducted in patients and that it provides abundant information regarding plaque microscopic morphology, which is essential to the identification and study of high-risk lesions. Even though many basic biological, clinical, and technological challenges must be addressed prior to widespread use of this technology, the unique capabilities of OCT ensure that it will have a prominent role in shaping the future of cardiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.