ArticleJournal of bacteriology2006
Helicobacter pylori initiates the stringent response upon nutrient and pH downshift.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 54 citations in OpenAlex.
- Omega stabilizes RNA polymerase condensates and contributes to cellular fitness during acid stress.bioRxiv : the preprint server for biology · 2026Article
- Article
- Article
- Review
- Emergence of metabolic coupling to the heterotrophISME communications · 2024Article
- Biofilm ofAntibiotics (Basel, Switzerland) · 2023Review
- SpoT-mediated NapA upregulation promotes oxidative stress-inducedAntimicrobial agents and chemotherapy · 2023Article
- Mutating bothFrontiers in microbiology · 2023Article
- Article
- Pathophysiology of enteropathogenicJournal of veterinary science · 2022Review
- Identification of a RelA/SpoT Homolog and Its Possible Role in the Accumulation of Astaxanthin inFrontiers in plant science · 2022Article
- In Silico Screening and In Vitro Assessment of Natural Products with Anti-Virulence Activity againstMolecules (Basel, Switzerland) · 2021Article
- What Flips the Switch? Signals and Stress Regulating Extraintestinal PathogenicMicroorganisms · 2021Review
- Primary antibiotic resistance of Helicobacter pylori isolates is twofold more frequent in HIV-positive than HIV-negative individuals: A descriptive observational study.MicrobiologyOpen · 2021Observational
- Nutrient Deficiency Promotes the Entry ofBiology · 2021Article
- A Stringent-Response-Defective Bradyrhizobium diazoefficiens Strain Does Not Activate the Type 3 Secretion System, Elicits an Early Plant Defense Response, and Circumvents NHApplied and environmental microbiology · 2021Article
- (p)ppGpp and Its Role in Bacterial Persistence: New Challenges.Antimicrobial agents and chemotherapy · 2020Review
- Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.The FEBS journal · 2020Article
- Synthesis of ppGpp impacts type IX secretion and biofilm matrix formation in Porphyromonas gingivalis.NPJ biofilms and microbiomes · 2020Article
- Clinical and laboratory importance of detectingPrzeglad gastroenterologiczny · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Helicobacter pylori was previously reported to lack a stringent response. In contrast, we show that after nutrient downshift, H. pylori produced abundant ppGpp and less total RNA. pH downshift also caused (p)ppGpp accumulation. Our observations indicate that nutrient deprivation and acid shock activate the stringent response in H. pylori.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.